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anti-Human ADK Antikörper:
anti-Mouse (Murine) ADK Antikörper:
anti-Rat (Rattus) ADK Antikörper:
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Human Polyclonal ADK Primary Antibody für ICC, IF - ABIN4278490
Liao, Lin, Kuo: Effect of high-fat diet on hepatic proteomics of hamsters. in Journal of agricultural and food chemistry 2015
Human Polyclonal ADK Primary Antibody für IHC (p), WB - ABIN391132
Mathews, Erion, Ealick: Structure of human adenosine kinase at 1.5 A resolution. in Biochemistry 1998
Show all 3 Pubmed References
Adenosine kinase contributes to cytokinin homeostasis
Increased cytokinin-responsive promoter activity in Arabidopsis plant tissue may therefore be a consequence of an ADK/AL2/C2 interaction.
The results of this study showed that over-expression of the major adenosine removing enzyme ADK in reactive astrocytes and subpopulation of remaining neurons in Rasmussen Encephalitis patients plays an important role in the epileptogensis of Rasmussen Encephalitis.
ADA (zeige ADA Antikörper) and ADK are involved in glioma progression; increased ADA (zeige ADA Antikörper) and ADK levels in peritumoral tissues may be associated with epilepsy in glioma patients.
The results of this study suggest that upregulation of ADK is a common pathologic component of FCDIIB.
These results suggest that upregulation of ADK is a common pathologic hallmark of Rasmussen encephalitis and that ADK might be a target in the treatment of epilepsy associated with Rasmussen encephalitis.
Data show that we a significantly higher expression of ADK in the peritumoral infiltrated tissue of patients with epilepsy than in patients without epilepsy.
The results of this study suggested that dysregulation of ADK in astrocytes is a common pathologic hallmark of temporal lobe epilepsy.
The cytoplasmic isoform of adenosine kinase is sufficient to alter sleep physiology. ADK might orchestrate neurotransmitter pathways involved in the generation of electroencephlogram oscillations and regulation of sleep.
The catalytic properties, gene expression and protein levels of certain proteins involved in mitochondrial ATP synthesis, such as F1F0-ATPase (zeige DNAH8 Antikörper), ANT and AK, in human skin fibroblasts with trisomic karyotype, compared them with euploid fibroblasts.
Equilibrative nucleoside transporters (hENT1, hENT2) together with adenosine kinase and 5'-nucleotidase (zeige NT5E Antikörper) play a crucial role in the regulation of CFTR (zeige CFTR Antikörper) through an adenosine-dependent pathway in human airway epithelia.
role for HIF-1alpha (zeige HIF1A Antikörper) in transcriptional repression of AK in hypoxia
Here the authors show that pro-inflammatory stimuli lead to endothelial inflammation by increasing adenosine kinase expression, and that its knockdown in endothelial cells inhibits atherosclerosis and cerebral ischemic injury in mice.
ADK expression negatively regulates the adaptive beta-cell response to high-fat diet challenge.
Our data show that neurological phenotypes in ADK-deficient patients are intrinsic to ADK deficiency in the brain and that blocking A2AR (zeige ADORA2A Antikörper) activity therapeutically can attenuate neurological symptoms in ADK deficiency.
The findings of this study implicated a glial-neuronal circuit, mediated by Ado (zeige ADO Antikörper), neuronal AdoRA1 (zeige ADORA1 Antikörper), and glial AdK that can modulate sleep homeostasis in a manner influenced by glial metabolic state.
We conclude that ADK provides important upstream regulation of adenosine-based homeostatic function of the brain
Adenosine kinase inhibition selectively promotes rodent and porcine islet beta-cell replication
Knockdown of Adk can protect the brain from the effects of a stroke.
a complete absence of ADK led to abnormalities in hepatic adenosine metabolism and to the development of acute, severe neonatal hepatic steatosis.
adenosine kinase inhibition promotes survival of fetal adenosine deaminase (zeige ADA Antikörper)-deficient thymocytes by blocking dATP accumulation
Overexpression of adenosine kinase in discrete parts of the epileptic hippocampus may contribute to the development and progression of seizure activity.
This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene.
, adenosine kinase (short isoform)-like protein
, adenosine kinase
, Adenosine kinase
, adenosine kinase-like
, Adenosine 5'-phosphotransferase
, adenosine kinase S homeolog