ADK Antikörper (C-Term)

Produktnummer ABIN391132

Produktdetails anti-ADK Antikörper

Target: ADK (Adenosine Kinase (ADK))

Bindungsspezifität: AA 322-352, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ADK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-352 amino acids from the C-terminal region of human ADK.

Klon: RB05395

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-ADK Antikörper (ABIN391132)

Annes, Ryu, Lam, Carolan, Utz, Hollister-Lock, Arvanites, Rubin, Weir, Melton: "Adenosine kinase inhibition selectively promotes rodent and porcine islet ?-cell replication." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 10, pp. 3915-20, (2012) (PubMed).

Details zu ADK

Target: ADK (Adenosine Kinase (ADK))

Andere Bezeichnung: ADK (ADK Produkte)

Synonyme: AK antikoerper, ADK antikoerper, DDBDRAFT_0186795 antikoerper, DDBDRAFT_0230174 antikoerper, DDB_0186795 antikoerper, DDB_0230174 antikoerper, ATPADK1 antikoerper, F3G5.4 antikoerper, F3G5_4 antikoerper, adenosine kinase antikoerper, adk antikoerper, 2310026J05Rik antikoerper, 5033405D03Rik antikoerper, AI255373 antikoerper, AI987814 antikoerper, Ak antikoerper, adenosine kinase antikoerper, ATP:adenosine 5'-phosphotransferase antikoerper, Adenosine kinase antikoerper, adenosine kinase S homeolog antikoerper, ADK antikoerper, adk antikoerper, Adk antikoerper, CNN02130 antikoerper, LOC5572668 antikoerper, CMU_026370 antikoerper, adk.S antikoerper

Hintergrund: Adenosine kinase is an abundant enzyme in mammalian tissues. The enzyme catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Alternative splicing results in two transcript variants encoding different isoforms. Both isoforms of the enzyme phosphorylate adenosine with identical kinetics and both require Mg2+ for activity.

Molekulargewicht: 40545

Gen-ID: 132

NCBI Accession: NP_001114, NP_001189378, NP_001189379, NP_006712

UniProt: P55263

Pathways: Ribonucleoside Biosynthetic Process