anti-SRSF1 (SRSF1) Antikörper

Bezeichnung:: anti-serine/arginine-Rich Splicing Factor 1 Antikörper (SRSF1)

Auf www.antikoerper-online.de finden Sie aktuell 68 serine/arginine-Rich Splicing Factor 1 (SRSF1) Antikörper von 19 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SRSF1 Proteine (13) und SRSF1 Kits (11) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 100 SRSF1 Produkte verfügbar.

Synonyme:: 1110054N12Rik, 5730507C05Rik, 6330415C05Rik, AI482334, Asf, Asf1, AW491331, CG9383, dASF/SF2, dAsf1, DKFZp469K2419, Dmel\\CG9383, l(3)76BDq, Sf2, SF2p33, Sfrs1, sfrs1b, SRp30a, wu:fb80g05, zgc:65898, zgc:76897, zgc:111894

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	SRSF1	6426	Q07955
	SRSF1	110809	Q6PDM2
	SRSF1	689890
Alle Spezies anzeigen Weitere Synonyme anzeigen

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anti-Human SRSF1 Antikörper:

anti-Mouse (Murine) SRSF1 Antikörper:

anti-Rat (Rattus) SRSF1 Antikörper:

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Verknüpfte Pathways mit anti-SRSF1 Antikörper

Ribonucleoprotein Complex Subunit Organization

Weitere Produktkategorien zu SRSF1 Antikörper

Am meisten referenzierte anti-SRSF1 Antikörper

Human Polyclonal SRSF1 Primary Antibody für ICC, IF - ABIN4353084 : Brown, Dobrikov, Gromeier et al.: Mitogen-activated protein kinase-interacting kinase regulates mTOR/AKT signaling and controls the serine/arginine-rich protein kinase-responsive type 1 internal ribosome entry site-mediated ... in Journal of virology 2014 (PubMed)
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Cow (Bovine) Polyclonal SRSF1 Primary Antibody für IHC, WB - ABIN2779013 : Velazquez-Dones, Hagopian, Ma, Zhong, Zhou, Ghosh, Fu, Adams: Mass spectrometric and kinetic analysis of ASF/SF2 phosphorylation by SRPK1 and Clk/Sty. in The Journal of biological chemistry 2005 (PubMed)
Show all 2 Pubmed References

Weitere Antikörper gegen SRSF1 Interaktionspartner

Fruit Fly (Drosophila melanogaster) serine/arginine-Rich Splicing Factor 1 (SRSF1) Interaktionspartner

DLP (zeige DMD Antikörper) and ASF1 are part of a predeposition complex, which is recruited by XNP (zeige ATRX Antikörper) and is necessary to prevent DNA exposure in the nucleus.
ASF1 cellular levels are tightly controlled by distinct pathways and provide a molecular mechanism for post-translational regulation of dASF1 and hASF1a (zeige ASF1A Antikörper) by TLK (zeige TLK2 Antikörper) kinases.
dASF1 has a direct role in modifying chromatin structure during DNA replication and this function of dASF1 is important for the processivity of the replication machinery.
Asf1 is directed via interactions with sequence-specific complexes to mediate silencing of specific target genes.
Histone chaperones ASF1 and NAP1 (zeige NAP1L1 Antikörper) differentially modulate removal of active histone marks by LID-RPD3 (zeige HDAC1 Antikörper) complexes during NOTCH (zeige NOTCH1 Antikörper) silencing.

Human serine/arginine-Rich Splicing Factor 1 (SRSF1) Interaktionspartner

Authors showed that Mir505-3p was capable of inhibiting tumor proliferation driven by SRSF1 in two neural tumor cell lines, Neuro-2a (N2a) and U251, exclusively in serum-reduced condition. Authors observed that the protein level of SRSF1 was gradually promoted by increasing concentration of serum.
The present study suggested that the tumor suppressor miR30c may be involved in prostate cancer tumorigenesis, possibly via targeting ASF/SF2.
It has been proposed that SF2/ASF has a protective role against JC virus reactivation in multiple sclerosis patients.
Immune suppression of JC virus gene expression is mediated by SRSF1.
ASF/SF2 is identified as a splicing regulator (zeige PTBP2 Antikörper) of cyclin T1 (zeige CCNT1 Antikörper), which contributes to the control of the subsequent transcription events.
Findings suggest MALAT1 increases AKAP-9 (zeige AKAP9 Antikörper) expression by promoting SRPK1 (zeige SRPK1 Antikörper)-catalyzed SRSF1 phosphorylation in CRC (zeige CALR Antikörper) cells. These results reveal a novel molecular mechanism by which MALAT1 regulates AKAP-9 (zeige AKAP9 Antikörper) expression in CRC (zeige CALR Antikörper) cells.
high level of SF2, as a novel oncoprotein in RCC (zeige XRCC1 Antikörper), was significantly associated with poor survival in a large cohort of RCC (zeige XRCC1 Antikörper) specimens. Taken together, our study presents a road map for the prediction and validation of miR (zeige MLXIP Antikörper)-766-3p/SF2 axis and thus imparts a therapeutic way for further RCC (zeige XRCC1 Antikörper) progression.
The authors found that RNA recognition motif 1 (RRM1) in SRSF1 binds PP1 and represses its catalytic function through an allosteric mechanism.
We present a joint atomistic molecular dynamics (MD) and experimental study of two RRM-containing proteins bound with their single-stranded target RNAs, namely the Fox-1 (zeige A2BP1 Antikörper) and SRSF1 complexes.The simulations predict unanticipated specific participation of Arg142 at the protein-RNA interface of the SRFS1 complex, which is subsequently confirmed by NMR and ITC measurements
Using NMR spectroscopy with two separately expressed domains of SRSF1, we showed that several residues in the RNA-binding motif 2 interact with the N-terminal region of the RS domain (RS1 (zeige RS1 Antikörper)).

Mouse (Murine) serine/arginine-Rich Splicing Factor 1 (SRSF1) Interaktionspartner

SRSF1 is a key regulator of DBF4B (zeige DBF4 Antikörper) pre-mRNA splicing dysregulation in colon cancer. SRSF1 is required for cancer cell proliferation.
LncRNA MALAT1 is dysregulated in diabetic nephropathy and involved in high glucose-induced podocyte injury via its interplay with beta-catenin (zeige CTNNB1 Antikörper) and SRSF1.
Authors showed that Mir505-3p was capable of inhibiting tumor proliferation driven by SRSF1 in two neural tumor cell lines, Neuro-2a (N2a) and U251, exclusively in serum-reduced condition. Authors observed that the protein level of SRSF1 was gradually promoted by increasing concentration of serum.
This study showed that the splicing factor (zeige SLU7 Antikörper) kinase SRPK1 (zeige SRPK1 Antikörper) is a key regulator of spinal nociceptive processing in naive and nerve injured animals. We present evidence for a novel mechanism in which altered SRSF1 localization/function in neuropathic pain results in sensitization of spinal cord neurons.
The expression levels of three splicing factors, ESRP1 (zeige ESRP1 Antikörper), PTB (zeige PTBP1 Antikörper) and SF2/ASF, are significantly altered during cardiac hypertrophy in mice.
RRP1B suppresses metastatic progression by altering the transcriptome through its interaction with splicing regulators such as SRSF1
Deletion of RRM1 (zeige RRM1 Antikörper) eliminated the splicing activity of SRSF1 and thus cellular transformation.
Specific effects on regulated splicing by SR proteins SRSF1 and SRSF2 (zeige SRSF2 Antikörper) depends on a complex set of relationships with multiple other SR proteins in mammalian genomes.
Treatment with IL-17 (zeige IL17A Antikörper) prolongs the half-life of chemokine (zeige CCL1 Antikörper) CXCL1 (zeige CXCL1 Antikörper) mRNA via the adaptor TRAF5 (zeige TRAF5 Antikörper) and the splicing-regulatory factor SF2 (ASF).
analysis of the miRNA-mediated interaction between leukemia/lymphoma-related factor (LRF (zeige ZBTB7A Antikörper)) and alternative splicing factor/splicing factor (zeige SLU7 Antikörper) 2 (ASF/SF2) affects cell senescence and apoptosis

SRSF1 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins. Multiple transcript variants encoding different isoforms have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 13.

Alternative names and synonyms associated with SRSF1

anti-silencing factor 1 (asf1) Antikörper
serine/arginine-rich splicing factor 1 L homeolog (srsf1.L) Antikörper
serine and arginine rich splicing factor 1 (SRSF1) Antikörper
serine/arginine-rich splicing factor 1 (Srsf1) Antikörper
serine and arginine rich splicing factor 1 (Srsf1) Antikörper
serine/arginine-rich splicing factor 1b (srsf1b) Antikörper

1110054N12Rik Antikörper
5730507C05Rik Antikörper
6330415C05Rik Antikörper
AI482334 Antikörper
Asf Antikörper
Asf1 Antikörper
AW491331 Antikörper
CG9383 Antikörper
dASF/SF2 Antikörper
dAsf1 Antikörper
DKFZp469K2419 Antikörper
Dmel\\CG9383 Antikörper
l(3)76BDq Antikörper
Sf2 Antikörper
SF2p33 Antikörper
Sfrs1 Antikörper
sfrs1b Antikörper
SRp30a Antikörper
wu:fb80g05 Antikörper
zgc:65898 Antikörper
zgc:76897 Antikörper
zgc:111894 Antikörper

Bezeichner auf Proteinebene für SRSF1

, , , , , , , , , , , , , , , , , , , CG9383-PA CG9383-PB anti- silencing function 1 anti-silencing factor asf1-PA asf1-PB splicing factor, arginine/serine-rich 1 (splicing factor 2, alternate splicing factor) ASF-1 SR splicing factor 1 alternative-splicing factor 1 pre-mRNA-splicing factor SF2, P33 subunit splicing factor 2 splicing factor, arginine/serine-rich 1 splicing factor arginine/serine-rich 1 splicing factor, arginine/serine-rich 1B ASF/SF2 pre-mRNA-splicing factor SRp30a splicing factor, arginine/serine-rich 1 (ASF/SF2) serine/arginine-rich splicing factor 1B splicing factor, arginine/serine-rich 1b

GENE ID	SPEZIES
40141	Drosophila melanogaster
399226	Xenopus laevis
772264	Gallus gallus
6426	Homo sapiens
609693	Canis lupus familiaris
654327	Sus scrofa
615796	Bos taurus
110809	Mus musculus
689890	Rattus norvegicus
100173318	Pongo abelii
393565	Danio rerio

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