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RFWD3 Proteine

(Ring Finger and WD Repeat Domain 3 (RFWD3))
E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint. May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53. Plays a role in RPA-mediated DNA damage signaling and repair.

5 Treffer :

custom-made RFWD3 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Produktnummer ABIN7564595
 
custom-made RFWD3 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Produktnummer ABIN7555192
 
RFWD3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant ELISA, SDS, WB
Produktnummer ABIN7579222
 
custom-made RFWD3 Spezies: Maus Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB
Produktnummer ABIN3136488
 
custom-made RFWD3 Spezies: Human Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB
Produktnummer ABIN3094992
 
  • Typ Protein
    • Protein
  • Anwendung
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
  • Reaktivität
    • Human
    • Mouse
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Cell-free protein synthesis (CFPS)
    • HEK-293 Cells
    • Escherichia coli (E. coli)
  • Bindungsspezifität
    • AA 1-774
  • Konjugat
    • His tag
    • Strep Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • custom-made
  • Hersteller
    • antibodies-online

Aliase für RFWD3 Proteine

ring finger and WD repeat domain 3 (Rfwd3) Proteine
ring finger and WD repeat domain 3 (RFWD3) Proteine
BC027246 Proteine
RFWD3 Proteine
RGD1305243 Proteine
RNF201 Proteine
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