anti-FDPS (FDPS) Antikörper

Bezeichnung:: anti-Farnesyl Diphosphate Synthase Antikörper (FDPS)

Auf www.antikoerper-online.de finden Sie aktuell 114 Farnesyl Diphosphate Synthase (FDPS) Antikörper von 21 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen FDPS Kits (16) und FDPS Proteine (13) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 149 FDPS Produkte verfügbar.

Synonyme:: (2E, 16.m00760, 6030492I17Rik, Ac2-125, AI256750, CG12389, DDBDRAFT_0206220, DDBDRAFT_0215017, DDB_0206220, DDB_0215017, Dmel\\CG12389, DmFPPS, DmFPPSase, DmFPS, Fdpsl1, FPPS, fps, l(2)k06103, mKIAA1293, NCU01175.1, v(2)k03514

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	FDPS	2224	P14324
	FDPS	83791	P05369
	FDPS	110196	Q920E5
Alle Spezies anzeigen Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-FDPS (FDPS) Antikörper

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anti-Human FDPS Antikörper:

anti-Rat (Rattus) FDPS Antikörper:

anti-Mouse (Murine) FDPS Antikörper:

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Verknüpfte Pathways mit anti-FDPS Antikörper

Regulation of Muscle Cell Differentiation

Weitere Produktkategorien zu FDPS Antikörper

Am meisten referenzierte anti-FDPS Antikörper

Human Polyclonal FDPS Primary Antibody für IHC (p), WB - ABIN389054 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
Show all 8 Pubmed References
Human Polyclonal FDPS Primary Antibody für IF, IHC (p) - ABIN1882080 : Nomura, Miyajima, Sazuka, Tanaka, Kawarabayasi, Sato, Nagase, Seki, Ishikawa, Tabata et al.: Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature ... in DNA research : an international journal for rapid publication of reports on genes and genomes 1995 (PubMed)
Show all 4 Pubmed References

Weitere Antikörper gegen FDPS Interaktionspartner

Fruit Fly (Drosophila melanogaster) Farnesyl Diphosphate Synthase (FDPS) Interaktionspartner

mitochondrial targeting of FPS may be widespread among eukaryotes
Farnesyl diphosphate synthase (FPPS) of the dipteran Drosophila melanogaster has been cloned and its catalytic properties have been assessed.

Human Farnesyl Diphosphate Synthase (FDPS) Interaktionspartner

Farnesyl pyrophosphate (FPP (zeige FDFT1 Antikörper)) allosterically regulated the activity of farnesyl pyrophosphate synthase.
FPPS mediates TGF-beta1 (zeige TGFB1 Antikörper)-induced lung cancer cell invasion and epithelial-to-mesenchymal transition via the RhoA (zeige RHOA Antikörper)/Rock1 (zeige ROCK1 Antikörper) pathway.
Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase
These results are consistent with the previously proposed hypothesis that the allosteric pocket of human FPPS, located near the active site, plays a feed-back regulatory role for this enzyme.
our study indicated that DR patients have higher VEGF (zeige VEGFA Antikörper) levels than diabetic patients without retinopathy, and -2578A/C (rs699947) and +405C/G (rs2010963) may be important factors in determining serum VEGF (zeige VEGFA Antikörper) levels.
Results suggest that polymorphisms of the FDPS gene may influence the bone response to drugs targeting the mevalonate pathway, like statins.
A co-crystal structure of human farnesyl pyrophosphate synthase in complex with a bisphosphonate and two molecules of inorganic phosphate.
The results identify new classes of FPPS inhibitors, diterpenoids and sesquiterpenoids, that bind to the IPP (zeige IPP Antikörper) site and may be of interest as anticancer and antiinfective drug leads.
These observations suggest that an increase in the expression of endogenous FPPS could confer at least partial resistance to the pharmacological effect of N-BP drugs such as ZOL in vivo
LRP5 (zeige LRP5 Antikörper) and FDPS loci age-specifically affect skeletal traits in healthy fertile women.

Mouse (Murine) Farnesyl Diphosphate Synthase (FDPS) Interaktionspartner

Overexpression of FPPS aggravates myocardial ischemia/reperfusion injury in mice.
Farnesyl pyrophosphate synthase (FPPS) may function as a potent regulator in myocardial remodelling. The FPPS-regulated signalling pathway is relevant to the pathological changes in cardiac hypertrophy and heart failure.
identified a single putative direct repeat 4 (DR4 (zeige HLADRB4 Antikörper)) LXR (zeige NR1H3 Antikörper) response element in the FPS (zeige FES Antikörper) promoter isolated from immortalized murine astrocyte P11 (zeige S100A10 Antikörper)-5 cells

FDPS Antigen-Profil

Beschreibung des Gens

This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with FDPS

Farnesyl pyrophosphate synthase (Fpps) Antikörper
farnesyl diphosphate synthase (fdps) Antikörper
farnesyl diphosphate synthase L homeolog (fdps.L) Antikörper
farnesyl pyrophosphate synthase (MGG_08649) Antikörper
farnesyl pyrophosphate synthetase (TP03_0857) Antikörper
farnesyl pyrophosphate synthetase (Tb09.160.4300) Antikörper
farnesyl-pyrophosphate synthetase (fpp) Antikörper
farnesyl pyrophosphate synthetase (BBOV_I000120) Antikörper
FDP synthase (fps) Antikörper
Farnesyl pyrophosphate synthetase (fpps) Antikörper
farnesyl diphosphate synthase (FDPS) Antikörper
farnesyl diphosphate synthase (Fdps) Antikörper
farnesyl diphosphate synthetase (Fdps) Antikörper
farnesyl pyrophosphate synthase 1 (fps1) Antikörper

(2E Antikörper
16.m00760 Antikörper
6030492I17Rik Antikörper
Ac2-125 Antikörper
AI256750 Antikörper
CG12389 Antikörper
DDBDRAFT_0206220 Antikörper
DDBDRAFT_0215017 Antikörper
DDB_0206220 Antikörper
DDB_0215017 Antikörper
Dmel\\CG12389 Antikörper
DmFPPS Antikörper
DmFPPSase Antikörper
DmFPS Antikörper
Fdpsl1 Antikörper
FPPS Antikörper
fps Antikörper
l(2)k06103 Antikörper
mKIAA1293 Antikörper
NCU01175.1 Antikörper
v(2)k03514 Antikörper

Bezeichner auf Proteinebene für FDPS

, , , , , , , , , , , , , , , , , , , , , , , , , , , , , farnesyl pyrophosphate synthase CG12389-PA Fpps-PA farnesyl diphosphate synthase farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) farnesyl pyrophosphate synthetase Farnesyl pyrophosphate synthetase (2E,6E)-farnesyl diphosphate synthase FPP synthase FPP synthetase dimethylallyltranstransferase farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase geranyltranstransferase CR 39 cholesterol-regulated 39 kDa protein farnesyl diphosphate synthetase testis-specific farnesyl pyrophosphate synthetase FPS 6E)-farnesyl diphosphate synthase FPPS GRMZM2G168681 PCO074380 PCO074380(592) PCO074380_ov PCO074380b QBB18h08 geranylgeranyl-diphosphate synthase gnp_QBB18h08b gpm430b prenyltransferase

GENE ID	SPEZIES
36209	Drosophila melanogaster
548584	Xenopus (Silurana) tropicalis
735190	Xenopus laevis
2678891	Magnaporthe oryzae 70-15
3499793	Theileria parva strain Muguga
3660082	Trypanosoma brucei brucei strain 927/4 GUTat10.1
3877737	Neurospora crassa OR74A
5476865	Babesia bovis T2Bo
8621722	Dictyostelium discoideum AX4
100195349	Salmo salar
2224	Homo sapiens
83791	Rattus norvegicus
281156	Bos taurus
480129	Canis lupus familiaris
425061	Gallus gallus
110196	Mus musculus
541903	Zea mays

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