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anti-Human CXCL12 Antikörper:
anti-Mouse (Murine) CXCL12 Antikörper:
anti-Rat (Rattus) CXCL12 Antikörper:
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Human Monoclonal CXCL12 Primary Antibody für CyTOF, ELISA (Capture) - ABIN4899704
Villalba, Salvucci, Aoki, De La Luz Sierra, Gupta, Davis, Wyvill, Little, Yarchoan, Tosato: Serum inactivation contributes to the failure of stromal-derived factor-1 to block HIV-I infection in vivo. in Journal of leukocyte biology 2003
Show all 39 Pubmed References
Human Monoclonal CXCL12 Primary Antibody für FACS - ABIN4896548
Hoellenriegel, Zboralski, Maasch, Rosin, Wierda, Keating, Kruschinski, Burger: The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization. in Blood 2014
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Human Polyclonal CXCL12 Primary Antibody für IF (p), IHC (p) - ABIN1386329
Pei, Zeng, Han, Liao, Zhou, Li, Zhang, Liu, Zhang, Liu, Yao, Xu: Renal interstitial infiltration and tertiary lymphoid organ neogenesis in IgA nephropathy. in Clinical journal of the American Society of Nephrology : CJASN 2014
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Human Polyclonal CXCL12 Primary Antibody für ELISA, Func - ABIN4301060
Nistala, Habibi, Aroor, Sowers, Hayden, Meuth, Knight, Hancock, Klein, DeMarco, Whaley-Connell: DPP4 inhibition attenuates filtration barrier injury and oxidant stress in the zucker obese rat. in Obesity (Silver Spring, Md.) 2014
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Human Polyclonal CXCL12 Primary Antibody für EIA, Func - ABIN116229
Schlaepfer, Audigé, Joller, Speck: TLR7/8 triggering exerts opposing effects in acute versus latent HIV infection. in Journal of immunology (Baltimore, Md. : 1950) 2006
Human Polyclonal CXCL12 Primary Antibody für ELISA, WB - ABIN2476434
Prociv, Walker, Whitby: Human ectopic fascioliasis in Australia: first case reports. in The Medical journal of Australia 1992
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Human Polyclonal CXCL12 Primary Antibody für Func, IHC (p) - ABIN2476433
Nagasawa, Tachibana, Kishimoto: A novel CXC chemokine PBSF/SDF-1 and its receptor CXCR4: their functions in development, hematopoiesis and HIV infection. in Seminars in immunology 1998
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Cow (Bovine) Polyclonal CXCL12 Primary Antibody für WB - ABIN2774605
Sadir, Imberty, Baleux, Lortat-Jacob: Heparan sulfate/heparin oligosaccharides protect stromal cell-derived factor-1 (SDF-1)/CXCL12 against proteolysis induced by CD26/dipeptidyl peptidase IV. in The Journal of biological chemistry 2004
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Serum CXCL12, but not CXCR4 (zeige CXCR4 Antikörper), Is Associated with Head and Neck Squamous Cell Carcinomas.
The aim of the present study was to assess whether fibrosis markers, estrogen receptor (ER)alpha (zeige ESR1 Antikörper) and the stromal derived factor (SDF)1/CXC chemokine receptor type 4 (CXCR4 (zeige CXCR4 Antikörper)) axis are abnormally expressed in Intrauterine adhesions endometrium.
HIV-1 infectors with SDF-1 3'A polymorphism have a higher chance of developing late AIDS.
the SDF1/CXCR4 (zeige CXCR4 Antikörper) signaling pathway is involved in Lowintensity pulsed ultrasoundpromoted periodontal ligament stem cell migration.
These results suggest that SDF1 (e.g. presented on proteoglycans) can rapidly activate integrins in an allosteric manner by binding to site 2 in the absence of CXCR4 (zeige CXCR4 Antikörper). The allosteric integrin activation by SDF1 is a novel target for drug discovery
CXCL12 single nucleotide polymorphisms association with the risk of hypertension in Chinese Han population.
These results suggest a key role for the CXCR4 (zeige CXCR4 Antikörper)-CXCL12 chemokine axis in breast cancer progression and highlight the prognostic importance of this chemokine (zeige CCL1 Antikörper) axis for breast cancer survival.
serum SDF-1 is increased in and may be a potential useful marker for primary biliary cholangitis
disruption of the CXCR4 (zeige CXCR4 Antikörper)/CXCL12 axis by CXCR4 (zeige CXCR4 Antikörper) antagonist AMD3100 blocked the contribution of both cancer and stromal cells to the metastatic cascade in the liver.
SDF-1 alpha overexpression in bone marrow-derived stromal stem cells promotes bone generation as indicated by osteogenesis and angiogenesis.
these results demonstrate that a cross-talk exists between the TGF-beta1 (zeige TGFB1 Antikörper) and SDF-1 pathways in choroid-retinal endothelial cells
following optic nerve crush, the levels of endogenous SDF-1alpha and CXCR4 (zeige CXCR4 Antikörper) increase in the retina and optic nerve, where activated glial cells may act as a source of increased SDF-1alpha protein.
The CXCR7 (zeige CXCR7 Antikörper)/CXCR4 (zeige CXCR4 Antikörper)/CXCL12 axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.
superparamagnetic iron oxide nanoparticles also stimulated CXCR4 (C-X-C chemokine receptor type 4 (zeige CXCR4 Antikörper)) expression and CXCR4 (zeige CXCR4 Antikörper)-SDF-1 (Stromal cell-derived factor 1) signaling in mesenchymal stem cells.
This study regarding high SDF-1 levels in our mouse model of ototoxicity would play a major role in the development of therapeutic agents using MSC (zeige MSC Antikörper) homing.
CXCL12-CXCR4 (zeige CXCR4 Antikörper) signalling is essential for the correct patterning of aortic arches and pulmonary arteries during development.
Data (including data from studies in knockout mice) suggest that adipocyte autocrine function involving Sdf1 regulates insulin (zeige INS Antikörper) resistance; Sdf1 gene expression correlates with insulin (zeige INS Antikörper)-desensitized conditions in adipocytes but not other tissues (liver, skeletal muscle); adipocyte-specific ablation of Sdf1 enhances insulin (zeige INS Antikörper) sensitivity in adipose tissues and in whole body.
postnatal CXCL12 signaling promotes a specific interneuron circuit that inhibits medial prefrontal cortex activity
Study reports that stromal cell-derived factor-1alpha elevated or therapeutically administered in ischemic wounded tissue can stimulate both local endothelial cells (EC) and bone marrow-derived endothelial progenitor cells (EPC (zeige TCF21 Antikörper)) to express reciprocally E-selectin (zeige SELE Antikörper)/ligand pairs and thereby enhance EPC (zeige TCF21 Antikörper)-EC interactions.
suggest that miR (zeige MLXIP Antikörper)-155 modulates SHIP-1 (zeige INPP5D Antikörper) expression that subsequently affects CXCL12-CXCR4 (zeige CXCR4 Antikörper) signaling axis via Akt (zeige AKT1 Antikörper) activation
Authors produced recombinant CXCL12 and CXCL12(5-67) and evaluated their effect in murine adult NSCs migration and survival in vitro. We showed CXCL12(5-67) does not promote NSCs migration, but does induce cell death.
Study demonstrates that CXCR4 (zeige CXCR4 Antikörper)/CXCL12 axis can limit oxidative stress injury in hematopoietic stem cells (HSCs) by reducing mitochondrial oxidative stress. CXCL12 has a direct rescue effect on oxidative stress-induced (zeige SQSTM1 Antikörper) HSC (zeige FUT1 Antikörper) damage at the mitochondrial level.
a defect of CXCL12 promoter histone acetylation may represent an additional process participating in CXCL12 expression extinction in colon cancer
expression patterns of xSDF-1a, xCXCR4, and xCXCR7 during gastrulation; results suggest SDF-1 signaling supports migration of the mesendoderm cell cohort toward the animal pole and that activin/nodal signaling acts as a regulator of the expression of xSDF-1a and xCXCR4, but not xCXCR7
SDF-1/CXCR4 chemokine (zeige CCL1 Antikörper) signaling is involved in the migration and survival or in the differentiation of PGCs in Xenopus
A significant increase of stromal cell-derived factor-1alpha and CXCR4 was observed in protein extracts of idiopathic inflammatory myopathies in comparison with normal controls.
SDF-1 signaling is necessary for migrations of massive numbers of cells during gastrulation.
Polymorphisms in CXCL12 are significantly associated with immunological traits in Landrace piglets and have potential application value for marker-assisted selection of pig breeding with disease resistance.
The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1/CXCR4 (zeige CXCR4 Antikörper) axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration.
Findings indicate that stromal fibroblasts within mammary glands with mastitis contribute to EMT (zeige ITK Antikörper) and inflammatory responses of epithelial cells through the secretion of SDF-1, which could result in the inflammation spread and fibrosis within mammary gland.
There is a potential link between follicular SDF1/CXCR4 (zeige CXCR4 Antikörper) activation and the regulation of ovulation-related genes in cows and horses.
Polymorphism of intron 2 of the SDF1 gene in Galloway, Hereford, and Russian Black Pied cattle
Study demonstrates that forced expression of Sdf1a in the fish embryo during early development is an effective strategy to disrupt primordial germ cell migration and produce large populations of infertile fish.
miR (zeige MYLIP Antikörper)-126a directs lymphatic endothelial cell sprouting and extension by interacting with Cxcl12a-mediated chemokine (zeige CCL1 Antikörper) signaling and Vegfc (zeige VEGFC Antikörper)-Flt4 (zeige FLT4 Antikörper) signal axis.
filopodia distribution and their dynamics are dictated by the gradient of the chemokine (zeige CCL1 Antikörper) Cxcl12a.
SDF1a directly controls the migration of both leading and trailing edges of a tissue through the activation of two independent receptors, CXCR4b and CXCR7 (zeige CXCR7 Antikörper).
Prospective isolation and culture of sdf1(DsRed) perivascular cells demonstrated properties consistent with mesenchymal stem cells.
Study shows that the primordium generates an attractant gradient across itself by sequestering Sdf1a protein in its rear via Cxcr7 (zeige CXCR7 Antikörper)-mediated chemokine (zeige CCL1 Antikörper) uptake. This self-generated attractant gradient, combined with the route information provided by the stripe of sdf1a-expressing cells, then provides directional guidance to the migrating primordium.
gata4 (zeige GATA4 Antikörper) gene regulates sdf1a levels during early embryogenesis
These findings suggest an "attractive path" model in which migrating cells closely follow a dynamic SDF1a source that is refined on a transcript and protein level by miR (zeige MYLIP Antikörper)-430 and Cxcr7b, respectively.
sdf-1 expression and function in the adult zebrafish have important similarities to mammals
Expression of Cxcl12 and Cxclr4 in radial glial cells of the adult zebrafish brain supports important roles for the Cxcl12/Cxcr4 (zeige CXCR4 Antikörper) pair in brain development and functioning.
This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
intercrine reduced in hepatomas
, pre-B cell growth-stimulating factor
, stromal cell-derived factor 1
, chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)
, chemokine CXCL12/SDF-1ALPHA
, stromal cell-derived factor 1 isoform alpha
, stromal cell-derived factor 1 isoform gamma
, 12-O-tetradecanoylphorbol 13-acetate repressed protein 1
, pre-B-cell growth-stimulating factor
, thymic lymphoma cell-stimulating factor
, SDF-1 gamma
, Stromal cell-derived factor 1
, stromal cell-derived factor-1 gamma
, C-X-C motif chemokine 12
, stromal-derived factor 1
, chemokine ligand 12b
, stromal cell derived factor 1
, stromal cell-derived factor-1 beta
, CXC chemokine
, CXCL12 chemokine
, chemokine ligand 12
, unm t30516