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anti-Human CXCL12 Antikörper:
anti-Mouse (Murine) CXCL12 Antikörper:
anti-Rat (Rattus) CXCL12 Antikörper:
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Human Monoclonal CXCL12 Primary Antibody für CyTOF, ELISA (Capture) - ABIN4899705
Lisignoli, Cristino, Piacentini, Cavallo, Caplan, Facchini: Hyaluronan-based polymer scaffold modulates the expression of inflammatory and degradative factors in mesenchymal stem cells: Involvement of Cd44 and Cd54. in Journal of cellular physiology 2006
Show all 39 Pubmed References
Human Monoclonal CXCL12 Primary Antibody für CyTOF, ELISA (Capture) - ABIN4899704
Villalba, Salvucci, Aoki, De La Luz Sierra, Gupta, Davis, Wyvill, Little, Yarchoan, Tosato: Serum inactivation contributes to the failure of stromal-derived factor-1 to block HIV-I infection in vivo. in Journal of leukocyte biology 2003
Show all 39 Pubmed References
Human Polyclonal CXCL12 Primary Antibody für IF (p), IHC (p) - ABIN1386329
Pei, Zeng, Han, Liao, Zhou, Li, Zhang, Liu, Zhang, Liu, Yao, Xu: Renal interstitial infiltration and tertiary lymphoid organ neogenesis in IgA nephropathy. in Clinical journal of the American Society of Nephrology : CJASN 2014
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Human Polyclonal CXCL12 Primary Antibody für ELISA, Func - ABIN4301060
Nistala, Habibi, Aroor, Sowers, Hayden, Meuth, Knight, Hancock, Klein, DeMarco, Whaley-Connell: DPP4 inhibition attenuates filtration barrier injury and oxidant stress in the zucker obese rat. in Obesity (Silver Spring, Md.) 2014
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Human Monoclonal CXCL12 Primary Antibody für FACS - ABIN4896548
Hoellenriegel, Zboralski, Maasch, Rosin, Wierda, Keating, Kruschinski, Burger: The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization. in Blood 2014
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Human Polyclonal CXCL12 Primary Antibody für EIA, Func - ABIN116229
Schlaepfer, Audigé, Joller, Speck: TLR7/8 triggering exerts opposing effects in acute versus latent HIV infection. in Journal of immunology (Baltimore, Md. : 1950) 2006
Cow (Bovine) Polyclonal CXCL12 Primary Antibody für WB - ABIN2774605
Sadir, Imberty, Baleux, Lortat-Jacob: Heparan sulfate/heparin oligosaccharides protect stromal cell-derived factor-1 (SDF-1)/CXCL12 against proteolysis induced by CD26/dipeptidyl peptidase IV. in The Journal of biological chemistry 2004
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CXCL12 is involved in the pathogenesis and healing of H. pylori-induced peptic ulcer.
Together, these data indicate that different mechanisms govern the flow response across GSCs, but that within a single patient, there are subpopulations of GSCs that respond to flow via either CD44 (zeige CD44 Antikörper)- or CXCR4 (zeige CXCR4 Antikörper)-CXCL12 mechanisms.
Data indicate that a constitutively monomeric CXCL12 variant reproduced the G protein-dependent and beta-arrestin-dependent responses that are associated with normal CXCR4 (zeige CXCR4 Antikörper) signaling and lead to cell migration.
HS had no effects on the binding of CXCL12alpha to CXCR4 (zeige CXCR4 Antikörper) or its biological activity, suggesting that this polysaccharide controls CXCL12 in an isoform-specific manner.
The level of CXCR4 (zeige CXCR4 Antikörper) protein expression was significantly higher in all cellular compartments of the endometriotic lesions compared to control endometrium. CXCL12 protein expression was also higher in endometriotic lesions and was greatest in the epithelial compartment. CXCL12 was increased more in the condition media of cultured endometriosis than in controls as measured by ELISA.
CCR1 activation potently induces multiple myeloma PC migration toward CCL3 (zeige CCL3 Antikörper) while abrogating the multiple myeloma PC migratory response to CXCL12.
High CXCL12 expression is associated with gemcitabine resistance in pancreatic cancer.
CXCL12 expression may be a useful marker for predicting the outcome in patients with esophageal squamous cell carcinoma and is a potentially new therapeutic target
our findings indicate the functional role of HBx in regulating the stem-like properties of OV6(+) CSCs in HCC (zeige FAM126A Antikörper) through the MDM2 (zeige MDM2 Antikörper)/CXCL12/CXCR4 (zeige CXCR4 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) signaling axis, and identify HBx, MDM2 (zeige MDM2 Antikörper), CXCR4 (zeige CXCR4 Antikörper) and OV6 as a novel prognostic pathway and potential therapeutic targets for patients with HBV-related HCC (zeige FAM126A Antikörper) patients
study revealed that the CXCL12-CXCR4 (zeige CXCR4 Antikörper) interaction is crucial for stromal cell contact-mediated early B lymphoid and pDC (zeige PNKD Antikörper) differentiation from immature hematopoietic and early T lymphoid precursors with a multilineage differentiation potential but not for stromal cell contact-independent generation of early T lymphoid precursors.
these results demonstrate that a cross-talk exists between the TGF-beta1 (zeige TGFB1 Antikörper) and SDF-1 pathways in choroid-retinal endothelial cells
following optic nerve crush, the levels of endogenous SDF-1alpha and CXCR4 (zeige CXCR4 Antikörper) increase in the retina and optic nerve, where activated glial cells may act as a source of increased SDF-1alpha protein.
The CXCR7 (zeige CXCR7 Antikörper)/CXCR4 (zeige CXCR4 Antikörper)/CXCL12 axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.
endothelial CXCR7 (zeige CXCR7 Antikörper)+ cells regulate CXCL12 gradient direction by controlling concentrations near but not far from the vasculature.
This study showed that release of BMP-2 (zeige BMP2 Antikörper) and SDF-1alpha from heparinized MCM scaffolds allows for the reduction of the applied BMP-2 (zeige BMP2 Antikörper) concentration since SDF-1alpha seems to enhance the osteoinductive potential of BMP-2 (zeige BMP2 Antikörper).
The results of this study suggested that enhanced interaction between STAT3 (zeige STAT3 Antikörper) and p300 (zeige NOTCH1 Antikörper) mediated the epigenetic upregulation of CXCL12 in dorsal horn neurons, which contributed to the antitubulin chemotherapeutics-induced persistent pain
Dipeptidyl peptidase-4 (zeige DPP4 Antikörper) inhibition, independent of glucagon-like peptide-1 receptor (zeige GLP1R Antikörper) signaling, contributes to protection of the diabetic kidney through SDF-1-dependent antioxidative and antifibrotic effects and amelioration of adverse renal hemodynamics.
High Cxcl12 expression is associated with Prostate Cancer.
Authors demonstrate that targeting the SDF-1/CXCR4 (zeige CXCR4 Antikörper) pathway in the context of KLF10 (zeige KLF10 Antikörper) deletion substantially suppresses PDAC progression
Adipocytes promoted osteoclast differentiation, function and expression of adhesion-related molecules through the CXCL12/CXCR4 (zeige CXCR4 Antikörper) signalling pathway.
these findings demonstrate that expression of Hmga2 cooperates with Jak2 (zeige JAK2 Antikörper)(V617F) in the pathogenesis of Mmyelofibrosis.
Data demonstrated that sustained expression of CXCL12 by MSCs in the primary tumour site inhibits metastasis through reduction of CXCR7 (zeige CXCR7 Antikörper), while, in the presence of TGFbeta (zeige TGFB1 Antikörper), this CXCL12 effect of MSCs on tumour cells is relieved.
CXCL12 upregulation prior to stroke onset, and its actions following stroke, contribute to the endogenous, anti-inflammatory phenotype induced by repetitive hypoxic preconditioning
expression patterns of xSDF-1a, xCXCR4, and xCXCR7 during gastrulation; results suggest SDF-1 signaling supports migration of the mesendoderm cell cohort toward the animal pole and that activin/nodal signaling acts as a regulator of the expression of xSDF-1a and xCXCR4, but not xCXCR7
SDF-1/CXCR4 chemokine (zeige CCL1 Antikörper) signaling is involved in the migration and survival or in the differentiation of PGCs in Xenopus
A significant increase of stromal cell-derived factor-1alpha and CXCR4 was observed in protein extracts of idiopathic inflammatory myopathies in comparison with normal controls.
SDF-1 signaling is necessary for migrations of massive numbers of cells during gastrulation.
Polymorphisms in CXCL12 are significantly associated with immunological traits in Landrace piglets and have potential application value for marker-assisted selection of pig breeding with disease resistance.
The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1/CXCR4 (zeige CXCR4 Antikörper) axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration.
There is a potential link between follicular SDF1/CXCR4 (zeige CXCR4 Antikörper) activation and the regulation of ovulation-related genes in cows and horses.
Polymorphism of intron 2 of the SDF1 gene in Galloway, Hereford, and Russian Black Pied cattle
Study demonstrates that forced expression of Sdf1a in the fish embryo during early development is an effective strategy to disrupt primordial germ cell migration and produce large populations of infertile fish.
miR (zeige MYLIP Antikörper)-126a directs lymphatic endothelial cell sprouting and extension by interacting with Cxcl12a-mediated chemokine (zeige CCL1 Antikörper) signaling and Vegfc (zeige VEGFC Antikörper)-Flt4 (zeige FLT4 Antikörper) signal axis.
filopodia distribution and their dynamics are dictated by the gradient of the chemokine (zeige CCL1 Antikörper) Cxcl12a.
SDF1a directly controls the migration of both leading and trailing edges of a tissue through the activation of two independent receptors, CXCR4b and CXCR7 (zeige CXCR7 Antikörper).
Prospective isolation and culture of sdf1(DsRed) perivascular cells demonstrated properties consistent with mesenchymal stem cells.
Study shows that the primordium generates an attractant gradient across itself by sequestering Sdf1a protein in its rear via Cxcr7 (zeige CXCR7 Antikörper)-mediated chemokine (zeige CCL1 Antikörper) uptake. This self-generated attractant gradient, combined with the route information provided by the stripe of sdf1a-expressing cells, then provides directional guidance to the migrating primordium.
gata4 (zeige GATA4 Antikörper) gene regulates sdf1a levels during early embryogenesis
These findings suggest an "attractive path" model in which migrating cells closely follow a dynamic SDF1a source that is refined on a transcript and protein level by miR (zeige MYLIP Antikörper)-430 and Cxcr7b, respectively.
sdf-1 expression and function in the adult zebrafish have important similarities to mammals
Expression of Cxcl12 and Cxclr4 in radial glial cells of the adult zebrafish brain supports important roles for the Cxcl12/Cxcr4 (zeige CXCR4 Antikörper) pair in brain development and functioning.
This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
intercrine reduced in hepatomas
, pre-B cell growth-stimulating factor
, stromal cell-derived factor 1
, chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)
, chemokine CXCL12/SDF-1ALPHA
, stromal cell-derived factor 1 isoform alpha
, stromal cell-derived factor 1 isoform gamma
, 12-O-tetradecanoylphorbol 13-acetate repressed protein 1
, pre-B-cell growth-stimulating factor
, thymic lymphoma cell-stimulating factor
, SDF-1 gamma
, Stromal cell-derived factor 1
, stromal cell-derived factor-1 gamma
, C-X-C motif chemokine 12
, stromal-derived factor 1
, chemokine ligand 12b
, stromal cell derived factor 1
, stromal cell-derived factor-1 beta
, CXC chemokine
, CXCL12 chemokine
, chemokine ligand 12
, unm t30516