PGAM1 Proteine (PGAM1)

Bezeichnung:: phosphoglycerate Mutase 1 (Brain) Proteine (PGAM1)

Auf www.antikoerper-online.de finden Sie aktuell 18 phosphoglycerate Mutase 1 (Brain) (PGAM1) Proteine von 8 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PGAM1 Antikörper (73) und PGAM1 Kits (27) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 125 PGAM1 Produkte verfügbar.

Synonyme:: 2310050F24Rik, MGC81450, Pgam-1, PGAM-B, pgam1, PGAMA, Pgmut, wu:fb81h05

alle Proteine anzeigen	Gen	GeneID	UniProt
	PGAM1	5223	P18669
	PGAM1	24642	P25113
	PGAM1	18648	Q9DBJ1
Weitere Synonyme anzeigen

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Verknüpfte Pathways mit PGAM1 Proteine

Regulation of Carbohydrate Metabolic Process

Weitere Produktkategorien zu PGAM1 Protein

Am meisten referenzierte PGAM1 Proteine

Human PGAM1 Protein expressed in Wheat germ - ABIN1314779 : Kimura, Sakurai, Koumura, Yamada, Hayashi, Tanaka, Hozumi, Tanaka, Takemura, Seishima, Inuzuka: High prevalence of autoantibodies against phosphoglycerate mutase 1 in patients with autoimmune central nervous system diseases. in Journal of neuroimmunology 2010 (PubMed)

Weitere Proteine zu PGAM1 Interaktionspartnern

Mouse (Murine) phosphoglycerate Mutase 1 (Brain) (PGAM1) Interaktionspartner

PGAM1 correlates with spermatogenic dysfunction and affects the function of cell proliferation, apoptosis and migration.
9630033F20Rik (zeige C12orf5 Proteine) may play an important role in muscle wasting and that it has a distinguished characterization of gene network.[9630033F20Rik (zeige C12orf5 Proteine)]
histidine-phosphorylated PGAM1 correlated with expression of PKM2 in tumor tissues; decreased pyruvate kinase activity in PKM2-expressing cells allows PEP-dep (zeige PREP Proteine)endent histidine phosphorylation of PGAM1 and may provide an alternate glycolytic pathway

Human phosphoglycerate Mutase 1 (Brain) (PGAM1) Interaktionspartner

When BPGM (zeige BPGM Proteine) is knocked out, 1,3-BPG can directly phosphorylate PGAM1. In this case, PGAM1 phosphorylation and activity are decreased, but nevertheless sufficient to maintain normal glycolytic flux and cellular growth rate.
study provided the first evidence revealing a non-metabolic function of PGAM1 in promoting cell migration, and gained new insights into the role of PGAM1 in cancer progression.
Data show that tyrosine 26 phosphorylation enhances the binding of phosphoglycerate mutase 1 (PGAM1) to its substrates through generating electrostatic environment and structural features that are advantageous to the binding.
PGAM1 in promoting homologous recombination repair in tumor cell lines. Suggest potential therapeutic opportunity for PGAM1 inhibitors in combination with PARP inhibitors in cancer treatment.
PGAM1 may be associated with the grade of glioma and be involved in the biological behavior of glioma cells. PGAM1 might be a novel therapeutic target in glioma.
PGAM1 correlates with spermatogenic dysfunction and affects the function of cell proliferation, apoptosis and migration.
Our finding showed that PGAM1 might serve as a promising therapeutic target for UBC (zeige RPS27A Proteine).
PGAM1 is highly expressed in clear cell renal cell carcinoma (zeige MOK Proteine) and correlated with clinicalpathological features, which may contribute to tumor formation and progression.
PGAM is acetylated at lysines 100/106/113/138 in its central region, and a member of the Sirtuin (zeige SIRT1 Proteine) family (class III deacetylase), SIRT2 (zeige SIRT2 Proteine), is responsible for its deacetylation.
Tyrosine26 phosphorylation represents an additional acute mechanism underlying phosphoglycerate mutase 1 upregulation.

PGAM1 Protein Überblick

Protein Überblick

Phosphoglyceric acid mutase (EC 2.7.5.3) is widely distributed in mammalian tissues where it catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway (summary by Chen et al., 1974

Alternative names and synonyms associated with PGAM1

phosphoglycerate mutase 1 (PGAM1)
phosphoglycerate mutase 1 (Pgam1)
phosphoglycerate mutase 1 L homeolog (pgam1.L)
phosphoglycerate mutase 1 (pgam1)
phosphoglycerate mutase 1a (pgam1a)

2310050F24Rik Protein
MGC81450 Protein
Pgam-1 Protein
PGAM-B Protein
pgam1 Protein
PGAMA Protein
Pgmut Protein
wu:fb81h05 Protein

Bezeichner auf Proteinebene für PGAM1

BPG-dependent PGAM 1 , phosphoglycerate mutase 1 , phosphoglycerate mutase A, nonmuscle form , phosphoglycerate mutase isozyme B , PGAM-B , phosphoglycerate mutase 1 (brain) , uncharacterized protein LOC706211 , bisphosphoglycerate mutase 1a

GENE ID	SPEZIES
5223	Homo sapiens
24642	Rattus norvegicus
404148	Bos taurus
428969	Gallus gallus
432058	Xenopus laevis
450650	Pan troglodytes
477786	Canis lupus familiaris
706211	Macaca mulatta
100144939	Xenopus (Silurana) tropicalis
100174215	Pongo abelii
18648	Mus musculus
100718830	Cavia porcellus
100154776	Sus scrofa
100352195	Oryctolagus cuniculus
323107	Danio rerio
101671017	Mustela putorius furo

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Show all phosphoglycerate Mutase 1 (Brain) Proteine (PGAM1) with Pubmed References

Mouse (Murine) phosphoglycerate Mutase 1 (Brain) (PGAM1) Interaktionspartner

Human phosphoglycerate Mutase 1 (Brain) (PGAM1) Interaktionspartner

Protein Überblick

Alternative names and synonyms associated with PGAM1

Bezeichner auf Proteinebene für PGAM1