RASSF1 Produkte
(Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
Kategorien
This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011].
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Ausgewählte RASSF1 Kategorien
RASSF1 Antikörper
High quality antibodies with extensive validation data.
RASSF1 ELISA Kits
Reliable ELISA kits for a wide range of species.
RASSF1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene RASSF1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (2)
- (4)
Kat. Nr.
ABIN673764
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN6264654
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
IF, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7256220
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene RASSF1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6959049
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1154468
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene RASSF1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN1098704
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1317520
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1317522
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren RASSF1 Produkten
: "An association between overexpression of DNA methyltransferase 3B4 and clear cell renal cell carcinoma." in: Oncotarget, Vol. 8, Issue 12, pp. 19712-19722, (2017) (PubMed).: "Comparison of Selected Protein Levels in Tumour and Surgical Margin in a Group of Patients with Oral Cavity Cancer." in: Biochemical genetics, Vol. 55, Issue 4, pp. 322-334, (2017) (PubMed).
: "CpG island promoter hypermethylation of Ras association domain family 1A gene contributes to gastric carcinogenesis." in: Molecular medicine reports, Vol. 11, Issue 4, pp. 3039-46, (2015) (PubMed).
: "Decreased expression of RASSF1A tumor suppressor gene is associated with worse prognosis in clear cell renal cell carcinoma." in: International journal of oncology, Vol. 48, Issue 1, pp. 55-66, (2015) (PubMed).
: "The RASSF1A tumor suppressor regulates XPA-mediated DNA repair." in: Molecular and cellular biology, Vol. 35, Issue 1, pp. 277-87, (2014) (PubMed).
: "CpG island hypermethylation of multiple tumor suppressor genes associated with loss of their protein expression during rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine." in: Biochemical and biophysical research communications, Vol. 402, Issue 3, pp. 507-14, (2010) (PubMed).
: "Hypermethylation of RASSF1A in human and rhesus placentas." in: The American journal of pathology, Vol. 170, Issue 3, pp. 941-50, (2007) (PubMed).
: "Mapping geographic zones of cancer risk with epigenetic biomarkers in normal breast tissue." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 12, Issue 22, pp. 6626-36, (2006) (PubMed).
: "The tumor suppressor RASSF1A in human carcinogenesis: an update." in: Histology and histopathology, Vol. 20, Issue 2, pp. 645-63, (2005) (PubMed).
: "Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter." in: Molecular and cellular biology, Vol. 25, Issue 10, pp. 3923-33, (2005) (PubMed).
Synonyme und alternative Namen zu RASSF1
NPR2-like, GATOR1 complex subunit (NPRL2), Ras association (RalGDS/AF-6) domain family 1 (rassf1), Ras association domain family member 1 (RASSF1), putative rassf1 (Smp_157340), Ras association domain family member 1 L homeolog (rassf1.L), Ras association (RalGDS/AF-6) domain family member 1 (Rassf1), Ras association domain family member 1 (Rassf1), 123F2, AA536941, AU044980, NORE2A, RASSF1, RASSF1A, Rassf1A, Rassf1B, Rassf1C, RDA32, REH3P21, wu:fc17f02, zgc:92505, zgc:112224Bezeichner auf Proteinebene für RASSF1
- Ras association (RalGDS/AF-6) domain family 1
- Ras association (RalGDS/AF-6) domain family member 1
- ras association domain-containing protein 1
- Ras association domain family 1
- rassf1
- WUGSC:H_LUCA12.5
- cardiac-specific ras association domain family 1 protein
- pancreas-specific ras association domain family 1 protein
- tumor suppressor protein RDA32
- 123F protein
- RASSF1A tumor suppressor
- protein 123F2
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