RASSF1 Antikörper (AA 103-132)

Produktnummer ABIN1537724

Der Kaninchen Polyklonal anti-RASSF1 Antikörper wird verwendet zum Nachweis von RASSF1 in Proben von Human und Maus. Er wurde validiert für WB.

Kurzübersicht für RASSF1 Antikörper (AA 103-132) (ABIN1537724)

Target: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASSF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB22967

Produktdetails anti-RASSF1 Antikörper

Bindungsspezifität: AA 103-132

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RASSF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the Central region of human RASSF1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: RASSF1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu RASSF1

Target: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Andere Bezeichnung: RASSF1

Hintergrund: This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Molekulargewicht: 39219

Gen-ID: 11186

NCBI Accession: NP_001193886, NP_009113, NP_733830, NP_733831, NP_733832

UniProt: Q9NS23