PYCARD Produkte
(PYD and CARD Domain Containing (PYCARD))
Kategorien
This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm\; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte PYCARD Kategorien
PYCARD Antikörper
High quality antibodies with extensive validation data.
PYCARD ELISA Kits
Reliable ELISA kits for a wide range of species.
PYCARD Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PYCARD Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (1)
- (7)
Kat. Nr.
ABIN6146515
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (1)
- (7)
Kat. Nr.
ABIN3021617
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, FACS, ICC
Validierungen
- (7)
Kat. Nr.
ABIN5542580
Menge
0.1 mg
Datenblatt
Datenblatt
Empfohlene PYCARD ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969788
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969787
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6976147
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PYCARD Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1316968
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3089316
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3137154
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PYCARD Produkten
: "PM2.5 exposure impairs sperm quality through testicular damage dependent on NALP3 inflammasome and miR-183/96/182 cluster targeting FOXO1 in mouse." in: Ecotoxicology and environmental safety, Vol. 169, pp. 551-563, (2019) (PubMed).: "AIM2 gene silencing attenuates diabetic cardiomyopathy in type 2 diabetic rat model." in: Life sciences, Vol. 221, pp. 249-258, (2019) (PubMed).
: "Evaluation of Canonical Inflammasome Activation in Human Monocytes by Imaging Flow Cytometry." in: Frontiers in immunology, Vol. 10, pp. 1284, (2019) (PubMed).
: "NLRP3 inflammasome activation in platelets in response to sepsis." in: Physiological reports, Vol. 7, Issue 9, pp. e14073, (2019) (PubMed).
: "Ozone protects the rat lung from ischemia-reperfusion injury by attenuating NLRP3-mediated inflammation, enhancing Nrf2 antioxidant activity and inhibiting apoptosis." in: European journal of pharmacology, Vol. 835, pp. 82-93, (2018) (PubMed).
: "Oral Administration of Compound Probiotics Ameliorates HFD-Induced Gut Microbe Dysbiosis and Chronic Metabolic Inflammation via the G Protein-Coupled Receptor 43 in Non-alcoholic Fatty Liver Disease ..." in: Probiotics and antimicrobial proteins, (2018) (PubMed).
: "S. aureus Evades Macrophage Killing through NLRP3-Dependent Effects on Mitochondrial Trafficking." in: Cell reports, Vol. 22, Issue 9, pp. 2431-2441, (2018) (PubMed).
: "NLRP3 inflammasome expression in lipopolysaccharide-induced otitis media." in: Acta oto-laryngologica, Vol. 138, Issue 12, pp. 1061-1065, (2018) (PubMed).
: "Actin polymerization plays a significant role in asbestos-induced inflammasome activation in mesothelial cells in vitro." in: Histochemistry and cell biology, Vol. 147, Issue 5, pp. 595-604, (2018) (PubMed).
: "Human Parvovirus Infection of Human Airway Epithelia Induces Pyroptotic Cell Death by Inhibiting Apoptosis." in: Journal of virology, Vol. 91, Issue 24, (2017) (PubMed).
Synonyme und alternative Namen zu PYCARD
PYD and CARD domain containing (PYCARD), PYD and CARD domain containing (Pycard), PYD and CARD domain containing (pycard), 9130417A21Rik, ASC, Asc, asc1, CARD5, masc, TMS, TMS-1, TMS1, TNS1, zAsc, zgc:109874Bezeichner auf Proteinebene für PYCARD
- apoptosis-associated speck-like protein containing a CARD
- caspase recruitment domain-containing protein 5
- target of methylation-induced silencing 1
- PYD and CARD domain-containing protein
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