CCL3 Protein
Kurzübersicht für CCL3 Protein (ABIN935631)
Target
Alle CCL3 Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Sequenz
- APYGADTPTA CCFSYGRQIP RKFIADYFET SSLCSQPGVI FLTKRNRQIC ADPKETWVQE YITELELNA
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Produktmerkmale
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Purified recombinant Human MIP1 alpha protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract rat peritoneal macrophages using a concentration of 50.0-100.0 ng/mL. -
Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
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Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 1-92) protein (GST tag)
CCL3 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) (Active) protein (Biotin)CCL3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) (Active) proteinCCL3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Chemokine (C-C Motif) Ligand 3 (CCL3) protein (His tag)CCL3 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) (Active) protein (His tag)CCL3 Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 23-92) (Active) protein (His tag)CCL3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) protein (His tag)CCL3 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 27-92) protein (Fc Tag)CCL3 Spezies: Human Wirt: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) protein (His tag)CCL3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
Chemokine (C-C Motif) Ligand 3 (CCL3) proteinCCL3 Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant 95,00% SDS
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
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Buffer
- Supplied as a lyophilized powder.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- RT/-20 °C
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- CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
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Andere Bezeichnung
- MIP1 alpha
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Hintergrund
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Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ, with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and Mouse MIP-1 alpha and MIP-1 beta are active on human and Mouse hematopoietic cells.
Alternative Names: MIP-1 alpha protein, LD78 beta protein, MIP 1 alpha, CCL3 protein, MIP 1 alpha protein, MIP-1 alpha protein, MIP-1 alpha, Macrophage Inflammatory Protein-1 alpha protein, MIP1 alpha -
Molekulargewicht
- 7.8 kDa
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Autophagie
Target
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