CCL3 Protein (AA 24-92)
Kurzübersicht für CCL3 Protein (AA 24-92) (ABIN6952188)
Target
Alle CCL3 Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Applikation
Reinheit
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Proteineigenschaft
- AA 24-92
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Sequenz
- SLAADTPTAC CFSYTSRQIP QNFIADYFET SSQCSKPGVI FLTKRSRQVC ADPSEEWVQK YVSDLELSA
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Produktmerkmale
- Recombinant Human CCL3 (MIP-1alpha)
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Endotoxin-Niveau
- <0.01 EU per 1μg of the protein by the LAL method
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Biological Activity Comment
- EC50 = 0.2 nM determined by Migration Assay in cells expressing recombinant CCR5
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Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 1-92) protein (GST tag)
CCL3 Spezies: Human Wirt: Wheat germ Recombinant AP, AA, ELISA, WB
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) (Active) protein (Biotin)CCL3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) protein (His tag)CCL3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) (Active) protein (His tag)CCL3 Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 23-92) (Active) protein (His tag)CCL3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) protein (His tag)CCL3 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 27-92) protein (Fc Tag)CCL3 Spezies: Human Wirt: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) (Active) protein (His tag)CCL3 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 98 % as determined by reducing SDS-PAGE. CC Active
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. -
Haltbarkeit
- 12 months
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- CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
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Andere Bezeichnung
- CCL3 (MIP-1alpha)
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Hintergrund
- Macrophage inflammatory proteins 1-alpha (MIP1alpha)(CCL3) binds to cell surface receptors CCR1 and CCR5. It is proinflammatory, leading to chemotaxis and activation of immune cells. It also inhibits proliferation of hematopoietic stem cells. Moreover, by binding to one of the HIV coreceptors, CCR5, it suppresses HIV infection.
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Molekulargewicht
- 7.716 kDa
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UniProt
- P10147
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Autophagie
Target
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