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IL-15 Protein

Dieses Recombinant IL-15-Protein wird in Escherichia coli (E. coli) produziert.
Produktnummer ABIN935477

Kurzübersicht für IL-15 Protein (ABIN935477)

Target

Alle IL-15 (IL15) Proteine anzeigen
IL-15 (IL15) (Interleukin 15 (IL15))

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 28
  • 9
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Quelle

  • 40
  • 10
  • 9
  • 4
  • 1
  • 1
Escherichia coli (E. coli)

Reinheit

> 98 % pure
  • Produktmerkmale

    Purified recombinant Human IL15 protein
    Expression System: E.coli
    Bioactivity: The ED50 as determined by the dose-dependant stimulation of the proliferation of mouse CTLL-2 was found to be
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  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Kommentare

    Biological activity: The ED50 as determined by the dose-dependant stimulation of the proliferation of mouse CTLL-2 was found to be

    Testdurchführung

    Protein quantitation was carried out by two independent methods 1. UV spectroscopy at 280 nm using the absorbency value of 0.55 as the extinction coefficient for a 0.1 % (1 mg/mL) solution.
    2. Analysis by RP-HPLC, using a calibrated solution of IL-15 as a Reference Standard.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Reconstitute in sterile water at the stock concentration of at elast 0.1 mg/mL.

    Buffer

    Lyophilized from 20 mM Tris, pH 8.0.

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    RT/-20 °C
  • Target

    IL-15 (IL15) (Interleukin 15 (IL15))

    Andere Bezeichnung

    IL15

    Hintergrund

    Interleukin 15 (IL-15) is a cytokine with structural similarity to IL-2. Like IL-2, IL-15 binds to and signals through the IL-2/IL-15 beta chain (CD122) and the common gamma chain (gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es). This cytokine induces cell proliferation of natural killer cells, cells of the innate immune system whose principal role is to kill virally infected cells.
    Alternative Names: IL-15 protein, IL-15 protein, IL 15 protein, IL-15, IL 15, IL15, Interleukin 15 protein, MGC9721 protein, IL-15 protein, IL-T protein

    Pathways

    JAK-STAT Signalweg, Glycosaminoglycan Metabolic Process
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