IL-15 Protein (AA 49-162)
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- Target Alle IL-15 (IL15) Proteine anzeigen
- IL-15 (IL15) (Interleukin 15 (IL15))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 49-162
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Sequenz
- AA 49-162
- Reinheit
- >95 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Less than 0.1 EU per μg by the LAL method.
- Top Product
- Discover our top product IL15 Protein
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Interleukin 15 (IL15) protein
IL15 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by SEC-HPLC
Interleukin 15 (IL15) (AA 50-162) (Active) protein (His tag)IL15 Spezies: Human Wirt: Escherichia coli (E. coli) > 97 % AcA, CC Active
Interleukin 15 (IL15) (AA 49-162) protein (His-IF2DI Tag)IL15 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 15 (IL15) (AA 49-162) protein (His-IF2DI Tag)IL15 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 15 (IL15) (AA 1-162) protein (GST tag)IL15 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 15 (IL15) (AA 30-129) protein (GST tag)IL15 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 15 (IL15) (AA 49-162) (Active) protein (His tag)IL15 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant SDS, Func Active
Interleukin 15 (IL15) proteinIL15 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant
Interleukin 15 (IL15) (AA 49-162) (Active) protein (Fc Tag)IL15 Spezies: Maus Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 15 (IL15) (AA 49-162), (full length) protein (His tag)IL15 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant 90 % ELISA
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handhabung
- Please avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
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- Target
- IL-15 (IL15) (Interleukin 15 (IL15))
- Andere Bezeichnung
- IL-15 (IL15 Produkte)
- Synonyme
- IL15 Protein, AI503618 Protein, IL-15 Protein, interleukin 15 Protein, IL15 Protein, Il15 Protein
- Hintergrund
- Interleukin 15 is also known as IL15, IL-15, and is a cytokine with structural similarity to IL-2. Like IL-2, IL-15 binds to and signals through the IL-2/IL-15 beta chain (CD122) and the common gamma chain (gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es). This cytokine induces cell proliferation of natural killer cells, cells of the innate immune system whose principal role is to kill virally infected cells. Interleukin 15 (IL-15) regulates T and natural killer (NK) cell activation and proliferation. Survival signals that maintain memory T cells in the absence of antigen are provided by IL-15. This cytokine is also implicated in NK cell development. In rodent lymphocytes, IL-15 prevents apoptosis by inducing an apoptosis inhibitor, BCL2L1/BCL-x(L). IL-15 has been shown to enhance the anti-tumor immunity of CD8+ T cells in pre-clinical models. A phase I clinical trial to evaluate the safety, dosing, and anti-tumor efficacy of IL-15 in patients with metastatic melanoma and renal cell carcinoma (kidney cancer) has begun to enroll patients at the National Institutes of Health.
- Molekulargewicht
- 12.8 kDa
- Pathways
- JAK-STAT Signalweg, Glycosaminoglycan Metabolic Process
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