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IL-13 Protein

IL13 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Produktnummer ABIN935475
  • Target Alle IL-13 (IL13) Proteine anzeigen
    IL-13 (IL13) (Interleukin 13 (IL13))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 26
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 29
    • 16
    • 8
    • 7
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequenz
    MSPGPVPPST ALRELIEELV NITQNQKAPL CNGSMVWSIN LTAGMYCAAL ESLINVSGCS AIEKTQRMLS GFCPHKVSAG QFSSLHVRDT KIEVAQFVKD LLLHLKKLFR EGRFN
    Produktmerkmale
    Purified recombinant Human IL13 protein
    Expression System: E.coli
    Bioactivity: The ED50 as determined by the dose-dependent proliferation of TF-1 cells was ? 1.0 ng/mL, corresponding to a specific activity of ? 1 x 10^6 units/mg.
    Reinheit
    > 98 % pure
    Endotoxin-Niveau
    < 0.1 ng per μg (1 EU/μg).
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    Discover our top product IL13 Protein
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with sterile water not less than 100 μg/mL.
    Buffer
    Lyophilized with no additives.
    Konservierungsmittel
    Without preservative
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    RT/-20 °C
  • Target
    IL-13 (IL13) (Interleukin 13 (IL13))
    Andere Bezeichnung
    IL13 (IL13 Produkte)
    Synonyme
    IL13 Protein, IL-13 Protein, P600 Protein, Il-13 Protein, L13 Protein, interleukin 13 Protein, IL13 Protein, Il13 Protein
    Hintergrund
    IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL13 in mice resulted in impaired Th2 cell development and indicated an important role for IL13 in the expulsion of gastrointestinal parasites. IL13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL1beta, TNF-alpha, IL6 and IL8. IL13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL13 activity inhibits the pathophysiology of asthma.
    Alternative Names: IL-13 protein, IL13, NC300 protein, IL 13, Human P600 protein, Mouse protein, IL-13, IL-13 protein, IL 13 protein, Interleukin 13 protein
    Molekulargewicht
    12.5 kDa
    Pathways
    JAK-STAT Signalweg, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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