CNTF Protein
Kurzübersicht für CNTF Protein (ABIN935263)
Target
Alle CNTF Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Sequenz
- MAFTEHSPLT PHRRDLCSRS IWLARKLRSD LTALTESYVK HQGLNKNINL DSADGMPVAS TDQWSELTEA ERLQENLQAY RTFHVLLARL LEDQQVHFTP TEGDFHQAIH TLLLQVAAFA YQIEELMILL EYKIPRNEAD GMPINVGDGG LFEKKLWGLK VLQELSQWTV RSIHDLRFIS SHQTGIPARG SHYIANNKKM
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Produktmerkmale
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Purified recombinant Human CNTF protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent proliferation of human TF-1 cells is 5 x 10^5 units/mg. -
Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstitute in 5 M Sodium Phosphate, pH 7.5 to a concentration of 0.1- 1.0 mg/mL.
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Buffer
- Lyophilized from 5 mM NaPO4, pH 7.0, with 75 mM NaCl.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- CNTF (Ciliary Neurotrophic Factor (CNTF))
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Andere Bezeichnung
- CNTF
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Hintergrund
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CNTF is a potent neural factor that was originally characterized as a vital factor for the survival of chick ciliary neurons in vitro. CNTF is also important for the survival of other neural cell types including primary sensory neurons, motor neurons, basal forebrain neurons and type 2 astrocytes. CNTF is highly conserved across species and exhibits cross-species bioactivity.
Alternative Names: Ciliary Neurotrophic Factor protein -
Molekulargewicht
- 22.7 kDa
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Pathways
- JAK-STAT Signalweg
Target
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