SKP1 Protein (AA 1-160)

Produktnummer ABIN935072

Dieses Recombinant SKP1-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für SKP1 Protein (AA 1-160) (ABIN935072)

Target: SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 90 % pure

Produktdetails

Proteineigenschaft: AA 1-160

Sequenz: MPSIKLQSSD GEIFEVDVEI AKQSVTIKTM LEDLGMDDEG DDDPVPLPNV NAAILKKVIQ WCTHHKDDPP PPEDDENKEK RTDDIPVWDQ EFLKVDQGTL FELILAANYL DIKGLLDVTC KTVANMIKGK TPEEIRKTFN IKNDFTEEEE AQVGSTQFCL

Produktmerkmale: Purified recombinant Human SKP1 protein
Expression System: E.coli

Anwendungsinformationen

Applikationshinweise: SKP1 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 50 mM NaCl, and 10 % glycerol.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: RT/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Antigendetails

Target: SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

Andere Bezeichnung: SKP1

Hintergrund: S-phase kinase-associated protein 1, also known as SKP1, is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to proteins containing an F-box motif, such as cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin dependent proteolysis. It is also involved in the control of beta-catenin levels and the activity of beta-catenin dependent TCF transcription factors. Recombinant human SKP1 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: SKP-1, MGC34403 protein, Transcription elongation factor B protein, p19A protein, S-phase kinase-associated protein 1 isoform a Cyclin A/CDK2 associated p19 protein, SKP-1 protein, Organ of Corti protein 2 protein, EMC19 protein, S phase kinase associated protein 1 protein, SKP1A protein, SKP 1A protein, SKP 1 protein, OCP-II protein, MGC34403 protein, RNA polymerase II elongation factor like protein OCP2 protein, TCEB1L protein, OCPII protein, RNA polymerase II elongation factor like protein protein, SIII protein, OCP 2 protein, p19skp1 protein, S phase kinase associated protein 1A p19A protein, Transcription elongation factor B SIII polypeptide 1 like., Transcription Elongation Factor B 1 like protein, OCP II protein, SKP1, Cyclin A/CDK2 associated protein p19 protein, Skp 1 protein, SKP 1, OCP2 protein, OCP II protein protein, S phase kinase associated protein 1A protein

Molekulargewicht: 18 kDa (160 AA)

Pathways: Zellzyklus, Hedgehog Signalweg, Mitotic G1-G1/S Phases