BID Protein (AA 1-195)

Produktnummer ABIN934976

Dieses Recombinant BID-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für BID Protein (AA 1-195) (ABIN934976)

Target: BID (BH3 Interacting Domain Death Agonist (BID))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 95 % pure

Produktdetails

Proteineigenschaft: AA 1-195

Sequenz: MDCEVNNGSS LRDECITNLL VFGFLQSCSD NSFRRELDAL GHELPVLAPQ WEGYDELQTD GNRSSHSRLG RIEADSESQE DIIRNIARHL AQVGDSMDRS IPPGLVNGLA LQLRNTSRSE EDRNRDLATA LEQLLQAYPR DMEKEKTMLV LALLLAKKVA SHTPSLLRDV FHTTVNFINQ NLRTYVRSLA RNGMD

Produktmerkmale: Purified recombinant Human BID protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Anwendungsinformationen

Applikationshinweise: BID protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl, pH 8.0, containing 20 % glycerol.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: RT/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Antigendetails

Target: BID (BH3 Interacting Domain Death Agonist (BID))

Andere Bezeichnung: BID

Hintergrund: BID is a pro-apoptotic Bcl-2 protein containing only the BH3 domain. In response to apoptotic signaling, BID interacts with another Bcl-2 family protein, Bax, leading to the insertion of Bax into the outer mitochondrial membrane. Bax is believed to induce the opening of the mitochondrial voltage-dependent anion channel. This results in the release of cytochrome c and other pro-apoptotic factors from the mitochondria leading to activation of caspases. Recombinant BID protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: p22 BID., p13 BID protein, Apoptotic death agonist BID protein, BH3 interacting domain death agonist isoform 2 Apoptotic death agonist protein, Human BID coding sequence protein, BH3 interacting domain death agonist p11 protein, MGC42355 protein, p11 BID protein, BID isoform L(2) protein, OTTHUMP00000196197 protein, BH3 interacting domain death agonist p13 protein, MGC15319 protein, HGNC:1050 protein, BID protein, BH3 interacting domain death agonist protein, BID isoform ES(1b) protein, p15 BID protein, BH3 interacting domain death agonist p15 protein, BH3 interacting domain death agonist isoform 2 protein, Desmocollin type 4 protein, FP497 protein

Molekulargewicht: 21.9 kDa (195 AA)

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity