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PCNA Protein (AA 1-261)
PCNA
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % pure
SDS
Produktdetails
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Target
Alle PCNA Proteine anzeigen
PCNA
(Proliferating Cell Nuclear Antigen (PCNA))
Protein-Typ
Recombinant
Proteineigenschaft
AA 1-261
Spezies
Alle Spezies für PCNA Proteine
Human
Quelle
Alle Expressionssysteme für PCNA Proteine
Escherichia coli (E. coli)
Applikation
SDS-PAGE (SDS)
Sequenz
MFEARLVQGS ILKKVLEALK DLINEACWDI SSSGVNLQSM DSSHVSLVQL TLRSEGFDTY RCDRNLAMGV NLTSMSKILK CAGNEDIITL RAEDNADTLA LVFEAPNQEK VSDYEMKLMD LDVEQLGIPE QEYSCVVKMP SGEFARICRD LSHIGDAVVI SCAKDGVKFS ASGELGNGNI KLSQTSNVDK EEEAVTIEMN EPVQLTFALR YLNFFTKATP LSSTVTLSMS ADVPLVVEYK IADMGHLKYY LAPKIEDEEG S
Produktmerkmale
Purified recombinant Human PCNA protein Expression System: E.coli Molecular weight on SDS-PAGE will appear higher.
Reinheit
> 95 % pure
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
PCNA protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Supplied as a liquid in 20 mM Tris, pH 7.5, containing 0 mM EDTA, and 20 % glycerol.
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
RT/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
Antigendetails
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Target
PCNA
(Proliferating Cell Nuclear Antigen (PCNA))
Andere Bezeichnung
PCNA (PCNA Produkte )
Synonyme
PCNAR Protein, Pcna/cyclin Protein, pcna Protein, AO090003000846 Protein, 53/13 Protein, CG9193 Protein, DmPCNA Protein, Dmel\\CG9193 Protein, MUS209 Protein, Mus209 Protein, PCNA Protein, PCNA/mus209 Protein, Pcna Protein, dPCNA Protein, l(2)02448 Protein, l(2)56F Protein, l(2)56Fa Protein, l(2)s1534 Protein, cb16 Protein, fb36g03 Protein, wu:fa28e03 Protein, wu:fb36g03 Protein, pcna-A Protein, proliferating cell nuclear antigen Protein, DNA polymerase III sliding clamp Protein, Proliferating cell nuclear antigen Protein, Proliferating cell nuclear antigen-like Protein, proliferating cell nuclear antigen L homeolog Protein, proliferating cell nuclear antigen 1 Protein, PCNA Protein, Pcna Protein, pcna Protein, MMP_RS08810 Protein, ANI_1_512014 Protein, AOR_1_1500154 Protein, MGC53867 Protein, pcna.L Protein, pcna1 Protein, LOC106420145 Protein, pcn1 Protein
Hintergrund
PCNA (Proliferating Cell Nuclear protein) is found in the nucleus and is a cofactor of DNA polymerase delta. This protein is associated with DNA synthesis and repair. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. It appears during late G1- phase, S-phase of mitosis and persists until the end of the M-phase because of its long biological half-life. PCNA may be induced by UV irradiation, growth factors and eventually by neighbouring tumours. Recombinant human PCNA, was expressed in E. coli and purified by conventional chromatography techniques. Alternative Names: PCNA protein, , Proliferating cell nuclear protein protein, MGC8367 protein, Proliferating cell nuclear protein protein
Molekulargewicht
28 kDa (261 AA)
Pathways
Telomere Maintenance , DNA Reparatur , Mitotic G1-G1/S Phases , DNA Replication , Synthesis of DNA , Autophagie
Zuletzt angesehen
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