GLI1 Protein

Produktnummer ABIN7939787

Recombinant GLI1-Protein exprimiert in Baculovirus infected Insect Cells.

Kurzübersicht für GLI1 Protein (ABIN7939787)

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Applikation: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Produktdetails

Verwendungszweck: Recombinant GLI1 protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Recombinant GLI1 protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

Handhabung: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Antigendetails

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Andere Bezeichnung: GLI1

Hintergrund:

Protein Background: GLI1 (Zinc finger protein GLI1) acts as a transcriptional activator. Binds to the DNA consensus sequence 5'-GACCACCCA-3'. Regulates the transcription of specific genes during normal development. Plays a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling. Plays a role in cell proliferation and differentiation via its role in SHH signaling.

Short Description: Recombinant GLI1 protein was expressed in a baculovirus expression system as the full length protein (accession number NP_005260.1) with an C-terminal FLAG tag. The molecular weight of GLI1 is 119.6 kDa.

Aliases: GLI, Zinc Finger Protein GLI1, PAPA8, PPD1

Pathways: Hedgehog Signalweg, Dopaminergic Neurogenesis