M-CSF/CSF1 Protein
Kurzübersicht für M-CSF/CSF1 Protein (ABIN7866444)
Target
Alle M-CSF/CSF1 (CSF1) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Verwendungszweck
- Recombinant Human M-CSF Protein
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Sequenz
- MEEVSEYCSH MIGSGHLQSL QRLIDSQMET SCQITFEFVD QEQLKDPVCY LKKAFLLVQD IMEDTMRFRD NTPNAIAIVQ LQELSLRLKS CFTKDYEEHD KACVRTFYET PLQLLEKVKN VFNETKNLLD KDWNIFSKNC NNSFAECSSQ GHERQSEGS
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Spezifität
- Chromosomal location:1p21-p13
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Produktmerkmale
- Length (aa):159
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Endotoxin-Niveau
- < 0.1 ng/μg of protein (< 1EU/μg)
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Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) (Active) protein
CSF1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) protein (Fc Tag)CSF1 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) (Active) protein (His-Avi Tag)CSF1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) protein (His tag)CSF1 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) (Active) protein (His tag)CSF1 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) (Active) protein (Biotin,His-Avi Tag)CSF1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190), (Isoform 3) (Active) proteinCSF1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as analyzed by non-reducing SDS-PAGE. Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (Active) proteinCSF1 Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by SDS-PAGE Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) protein (mFc Tag)CSF1 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-187) (Active) proteinCSF1 Spezies: Maus Wirt: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
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Applikationshinweise
- The biological activity was determined by the dose-dependent induction of proliferation in NFS60 cells (Murine myeloid Leukemia cell line).
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- water
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Buffer
- PBS
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- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
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Andere Bezeichnung
- M-CSF
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Hintergrund
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Synonyms: CSF1, MCSF, CSF-1
Description: Granulocyte/Macrophage Colony-Stimulating Factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Macrophage Colony Stimulating Factor Human Recombinant produced in E. coli is a disulfide linked homodimer, non-glycosylated, polypeptide chain containing 2 x 159 amino acids and having a total molecular mass of 36.8 KD. M-CSF is purified by proprietary chromatographic techniques.
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Molekulargewicht
- 36.8 kDa
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Gen-ID
- 1435
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NCBI Accession
- NM_000757, NP_000748
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UniProt
- P09603
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Pathways
- RTK Signalweg
Target
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