BDNF Protein

Produktnummer ABIN7849701

Recombinant BDNF-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für BDNF Protein (ABIN7849701)

Target: BDNF (Brain-Derived Neurotrophic Factor (BDNF))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: >95 % by SDS-PAGE

Produktdetails

Verwendungszweck: Recombinant Human /Mouse/Rat BDNF Protein

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: <0.01EU/μg by LAL test

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration <100 μg/mL.)

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 400 mM NaCl, pH 7.2.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Antigendetails

Target: BDNF (Brain-Derived Neurotrophic Factor (BDNF))

Andere Bezeichnung: BDNF

Hintergrund:

Synonyms: Brain-derived neurotrophic factor, BDNF, brain-derived neurotrophic factor, ANON2, BULN2, brain derived neurotrophic factor

Description: Recombinant human BDNF is produced by the E.coli system, with the target gene encoding His129-Arg247 expressed.

Background: Brain-derived neurotrophic factor, also known as BDNF, is a prosurvival factor induced by cortical neurons that is necessary for survival of striatal neurons in the brain. BDNF is a member of the "neurotrophin" family of growth factors, which are related to the NGF. It acts on certain neurons of the central nervous system and the peripheral nervous system, helping to support the survival of existing neurons, and encourage the growth and differentiation of new neurons and synapses. In the brain, it is active in the hippocampus, cortex, and basal forebrain-areas vital to learning, memory, and higher thinking. Post mortem analysis has shown lowered levels of BDNF in the brain tissues of people with Alzheimer's disease.

UniProt: P23560

Pathways: RTK Signalweg, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity