IL-8 Protein
Kurzübersicht für IL-8 Protein (ABIN7849699)
Target
Alle IL-8 (IL8) Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
Reinheit
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Verwendungszweck
- Recombinant Human IL-8 Protein
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- <1 EU/μg by LAL test
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- IL-8 (IL8) (Interleukin 8 (IL8))
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Andere Bezeichnung
- IL-8
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Hintergrund
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Synonyms: CXCL8, chemokine (C-X-C motif) ligand 8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, IL8, C-X-C motif chemokine ligand 8, Interleukin-8, SCYB8
Description: Recombinant human IL-8 is produced by the mammalian system, with the target gene encoding Glu21-Ser99 expressed.
Background: Interleukin 8 (IL-8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cellsand endothelial cells. Endothelial cells store IL-8 in their storage vesicles, the Weibel-Palade bodies.In humans, the interleukin-8 protein is encoded by the CXCL8 gene.IL-8 is initially produced as a precursor peptide of 99 amino acids which then undergoes cleavage to create several active IL-8 isoforms.In culture, a 72 amino acid peptide is the major form secreted by macrophages.
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UniProt
- P10145
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Pathways
- TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagie
Target
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