GDNF Protein

Produktnummer ABIN7849696

Dieses Recombinant GDNF-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für GDNF Protein (ABIN7849696)

Target: GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: >95 % by SDS-PAGE

Produktdetails

Verwendungszweck: Recombinant Human GDNF Protein

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: <1 EU/μg by LAL test

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Antigendetails

Target: GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))

Andere Bezeichnung: GDNF

Hintergrund:

Synonyms: GDNF, ATF1, ATF2, glial cell derived neurotrophic factor, HFB1-HSCR3, ATF

Description: Recombinant human GDNF is produced by the E.coli system, with the target gene encoding Ser78-Ile211 expressed.

Background: Glial cell line-derived neurotrophic factor (GDNF) is a protein that, in humans, is encoded by the GDNF gene.GDNF is a small protein that potently promotes the survival of many types of neurons.It signals through GFRα receptors, particularly GFRα1. It is also responsible for the determination of spermatogonia into primary spermatocytes, i.e. it is received by RET proto-oncogene (RET) and by forming gradient with SCF it divides the spermatogonia into two cells. As the result there is retention of spermatogonia and formation of spermatocyte.

UniProt: P39905

Pathways: RTK Signalweg, Synaptic Membrane, Tube Formation, Autophagie, Smooth Muscle Cell Migration