Sclerostin Protein (SOST) (His tag)

Produktnummer ABIN7669713

Recombinant Sclerostin-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für Sclerostin Protein (SOST) (His tag) (ABIN7669713)

Target: Sclerostin (SOST)

Protein-Typ: Recombinant

Biologische Aktivität: Inactive

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 %

Produktdetails

Aufreinigungstag / Konjugat: Dieses Sclerostin Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human SOST protein (His tag)

Sequenz: Gln 24-Tyr 213

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 10 EU/mg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: Sclerostin (SOST)

Andere Bezeichnung: SOST

Hintergrund: Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST is asecreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain. It shows sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. SOST is produced by the osteocyte and has anti-anabolic effects on bone formation. It is a negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.,CDD,DAND6,SOST1,VBCH

Molekulargewicht:

calculated_mw: 20.8 kDa

observed_mw: 28 kDa

UniProt: Q9BQB4