Clusterin Protein (CLU) (His tag)

Produktnummer ABIN7668544

Dieses Recombinant Clusterin-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für Clusterin Protein (CLU) (His tag) (ABIN7668544)

Target: Clusterin (CLU)

Protein-Typ: Recombinant

Biologische Aktivität: Inactive

Spezies: Ratte

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 %

Produktdetails

Aufreinigungstag / Konjugat: Dieses Clusterin Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Rat Clusterin/ApoJ protein (His tag)

Sequenz: Glu 22-Arg 226

Aufreinigung: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 10 EU/mg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: Clusterin (CLU)

Andere Bezeichnung: Clusterin,ApoJ

Hintergrund: Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis, heart, ovary, adrenal gland, brain and liver. Clusterin has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. In addition,Clusterin is up/ down regulated on the mRNA or protein level in many pathological and clinically relevant situations including cancer, organ regeneration, infection, Alzheimer disease, retinitis pigmentosa, myocardial infarction, renal tubular damage, autoimmunity and others.,AAG4,AP,APOJ,Aging-Associated Gene 4 Protein,Apo-J,Apolipoprotein J,CLI,CLU,Clusterin,Complement Cytolysis Inhibitor,Complement-Associated Protein SP-40,KUB1,Ku70-Binding Protein 1,NA1/NA2,TRPM-2,Testosterone-Repressed Prostate Message 2

Molekulargewicht:

calculated_mw: 22.4 kDa

observed_mw: 28 kDa

UniProt: P05371

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling