HMGB1 Protein (AA 1-215) (His tag)

Produktnummer ABIN7607153

Dieses Recombinant HMGB1-Protein wird in Mammalian Cells exprimiert.

Kurzübersicht für HMGB1 Protein (AA 1-215) (His tag) (ABIN7607153)

Target: HMGB1 (High Mobility Group Box 1 (HMGB1))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Mammalian Cells

Applikation: Western Blotting (WB), SDS-PAGE (SDS), ELISA, Immunogen (Imm), Activity Assay (AcA)

Reinheit: >95 % as determined by SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 1-215

Aufreinigungstag / Konjugat: Dieses HMGB1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human HMGB1 Protein, C-His (Active)

Endotoxin-Niveau: <0.1 EU/μg of the protein by the LAL method.

Biological Activity Comment: Measured by its binding ability in a functional ELISA. Immobilized human HMGB1 (Cat #: AHC40301) at 2μg/mL (100 μL/well) can bind human AGER/RAGE with a linear range of 0.1-42.8 ng/mL.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from a solution in PBS pH 7.4, 5 % Trehalose, 5 % Mannitol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.

Haltbarkeit: 12 months

Antigendetails

Target: HMGB1 (High Mobility Group Box 1 (HMGB1))

Andere Bezeichnung: High mobility group protein B1

Hintergrund: High mobility group protein B1, HMGB1, HMG1, HMG-1, High mobility group protein 1

UniProt: P09429

Pathways: p53 Signalweg, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome