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HMGB1 Protein (AA 1-215) (GST tag)

HMGB1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Produktnummer ABIN1306797
  • Target Alle HMGB1 Proteine anzeigen
    HMGB1 (High Mobility Group Box 1 (HMGB1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-215
    Spezies
    • 27
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 22
    • 13
    • 9
    • 1
    • 1
    • 1
    • 1
    Wheat germ
    Aufreinigungstag / Konjugat
    Dieses HMGB1 Protein ist gelabelt mit GST tag.
    Applikation
    Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)
    Verwendungszweck
    HMGB1 (Human) Recombinant Protein (P01)
    Sequenz
    MGKGDPKKPR GKMSSYAFFV QTCREEHKKK HPDASVNFSE FSKKCSERWK TMSAKEKGKF EDMAKADKAR YEREMKTYIP PKGETKKKFK DPNAPKRPPS AFFLFCSEYR PKIKGEHPGL SIGDVAKKLG EMWNNTAADD KQPYEKKAAK LKEKYEKDIA AYRAKGKPDA AKKGVVKAEK SKKKKEEEED EEDEEDEEEE EDEEDEDEEE DDDDE
    Produktmerkmale
    Human HMGB1 full-length ORF ( AAH03378.1, 1 a.a. - 215 a.a.) recombinant protein with GST-tag at N-terminal.
    Aufreinigung
    in vitro wheat germ expression system
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Kommentare

    Preparation method: in vitro, wheat germ expression system
    Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
    Handhabung
    Aliquot to avoid repeated freezing and thawing.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Best use within three months from the date of receipt of this protein.
  • Yang, Lee, Song, Bae: "Ameliorative effect of a rarely occurring C-methylrotenoid on HMGB1-induced septic responses in vitro and in vivo." in: Biochemical pharmacology, Vol. 110-111, pp. 58-70, (2016) (PubMed).

    Fang, Jiang: "IL-1β/HMGB1 signalling promotes the inflammatory cytokines release via TLR signalling in human intervertebral disc cells." in: Bioscience reports, Vol. 36, Issue 5, (2016) (PubMed).

    Min, Ku, Park, Park, Lee, Bae: "Anti-septic effects of pelargonidin on HMGB1-induced responses in vitro and in vivo." in: Archives of pharmacal research, Vol. 39, Issue 12, pp. 1726-1738, (2016) (PubMed).

    Lee, Park, Kwak, Kim, Na, Bae: "PEGylated lysozymes with anti-septic effects in human endothelial cells and in mice." in: Biochemical and biophysical research communications, Vol. 459, Issue 4, pp. 662-7, (2015) (PubMed).

    Kwak, Ku, Kang, Baek, Bae: "Methylthiouracil, a new treatment option for sepsis." in: Vascular pharmacology, (2015) (PubMed).

    Tuan, Lee, Oh, Kulkarni, Gény, Jung, Kang, Bae, Na: "Flavanones and Chromones from Salicornia herbacea Mitigate Septic Lethality via Restoration of Vascular Barrier Integrity." in: Journal of agricultural and food chemistry, Vol. 63, Issue 46, pp. 10121-30, (2015) (PubMed).

    Lee, Ku, Bae: "Factor Xa inhibits HMGB1-induced septic responses in human umbilical vein endothelial cells and in mice." in: Thrombosis and haemostasis, Vol. 112, Issue 4, pp. 757-69, (2014) (PubMed).

    Ku, Lee, Kim, Bae: "Anti-septic effects of pellitorine in HMGB1-induced inflammatory responses in vitro and in vivo." in: Inflammation, Vol. 37, Issue 2, pp. 338-48, (2014) (PubMed).

    Ku, Kim, Bae: "Vascular barrier protective effects of piperlonguminine in vitro and in vivo." in: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 63, Issue 5, pp. 369-79, (2014) (PubMed).

    Lee, Ku, Yoo, Song, Bae: "Andrographolide inhibits HMGB1-induced inflammatory responses in human umbilical vein endothelial cells and in murine polymicrobial sepsis." in: Acta physiologica (Oxford, England), Vol. 211, Issue 1, pp. 176-87, (2014) (PubMed).

    Klawitter, Hakozaki, Kobayashi, Krupkova, Quero, Ospelt, Gay, Hausmann, Liebscher, Meier, Sekiguchi, Konno, Boos, Ferguson, Wuertz: "Expression and regulation of toll-like receptors (TLRs) in human intervertebral disc cells." in: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, Vol. 23, Issue 9, pp. 1878-91, (2014) (PubMed).

    Kwak, Ku, Han, Bae: "Vascular barrier protective effects of baicalin, baicalein and wogonin in vitro and in vivo." in: Toxicology and applied pharmacology, Vol. 281, Issue 1, pp. 30-38, (2014) (PubMed).

    Yang, Ku, Lee, Lee, Lee, Song, Bae: "Barrier protective effects of rosmarinic acid on HMGB1-induced inflammatory responses in vitro and in vivo." in: Journal of cellular physiology, Vol. 228, Issue 5, pp. 975-82, (2013) (PubMed).

    Lee, Ku, Kim, Bae: "Emodin-6-O-?-D-glucoside inhibits HMGB1-induced inflammatory responses in vitro and in vivo." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 52, pp. 97-104, (2013) (PubMed).

    Lee, Ku, Kim, Lee, Bae: "Inhibitory effects of epi-sesamin on HMGB1-induced vascular barrier disruptive responses in vitro and in vivo." in: Toxicology and applied pharmacology, Vol. 267, Issue 3, pp. 201-8, (2013) (PubMed).

    Lee, Ku, Lee, Bae: "Anti-septic effects of glyceollins in HMGB1-induced inflammatory responses in vitro and in vivo." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 63, pp. 1-8, (2013) (PubMed).

    Bae: "Effects of lower concentration thrombin on high-mobility group box 1 protein-mediated inflammatory responses." in: Inflammation, Vol. 35, Issue 3, pp. 1078-86, (2012) (PubMed).

    Kim, Ku, Bae: "Inhibitory effects of kaempferol-3-O-sophoroside on HMGB1-mediated proinflammatory responses." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 50, Issue 3-4, pp. 1118-23, (2012) (PubMed).

    Yang, Lee, Ku, Song, Bae: "Anti-inflammatory activities of oleanolic acid on HMGB1 activated HUVECs." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 50, Issue 5, pp. 1288-94, (2012) (PubMed).

    Lee, Ku, Bae, Bae: "Inhibitory effects of lycopene on HMGB1-mediated pro-inflammatory responses in both cellular and animal models." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 50, Issue 6, pp. 1826-33, (2012) (PubMed).

  • Target
    HMGB1 (High Mobility Group Box 1 (HMGB1))
    Andere Bezeichnung
    HMGB1 (HMGB1 Produkte)
    Synonyme
    HMG1 Protein, HMG3 Protein, SBP-1 Protein, DEF Protein, HMG-1 Protein, Hmg1 Protein, amphoterin Protein, p30 Protein, hmgb1 Protein, ik:tdsubc_1a5 Protein, wu:fb23c02 Protein, xx:tdsubc_1a5 Protein, zgc:56110 Protein, zgc:77104 Protein, hmg-1 Protein, hmg3 Protein, sbp-1 Protein, hmg1 Protein, HMGB1 Protein, Ac2-008 Protein, high mobility group box 1 Protein, high-mobility group box 1 Protein, high mobility group box 1a Protein, high mobility group box 1 L homeolog Protein, high mobility group protein B1 Protein, HMGB1 Protein, Hmgb1 Protein, hmgb1 Protein, hmgb1a Protein, hmgb1.L Protein, LOC100359149 Protein
    Hintergrund
    Full Gene Name: high-mobility group box 1
    Synonyms: DKFZp686A04236,HMG1,HMG3,SBP-1
    Gen-ID
    3146
    Pathways
    p53 Signalweg, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome
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