EPO Protein (AA 30-193) (Fc Tag)
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- Target Alle EPO Proteine anzeigen
- EPO (Erythropoietin (EPO))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 30-193
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Spezies
- Human
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Quelle
- CHO Cells
- Aufreinigungstag / Konjugat
- Dieses EPO Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- EPO (human):Fc (human) (rec.) (non-lytic)
- Kreuzreaktivität
- Human
- Produktmerkmale
- The extracellular domain of human EPO (aa 30-193) is fused to the N-terminus of the Fc region of a mutant human IgG1.
- Reinheit
- >98 % (SDS-PAGE)
- Sterilität
- Sterile filtered
- Endotoxin-Niveau
- <0.06EU/μg protein (LAL test, Lonza).
- Biological Activity Comment
- Measured by the dose-dependant stimulation of human megakaryoblastic leukemia cells.
- Top Product
- Discover our top product EPO Protein
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Erythropoietin (EPO) (AA 28-193) (Active) protein
EPO Spezies: Human Wirt: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Erythropoietin (EPO) (Active) protein (His tag)EPO Spezies: Maus Wirt: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
Erythropoietin (EPO) (AA 1-193) protein (GST tag)EPO Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Lyophilized from 0.2μm-filtered solution in PBS.
- Handhabung
- Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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- Target
- EPO (Erythropoietin (EPO))
- Andere Bezeichnung
- EPO (EPO Produkte)
- Substanzklasse
- Hormone
- Hintergrund
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Erythropoietin, Epoetin
Erythropoietin is the principal hormone involved in the regulation of erythropoiesis by stimulating the proliferation and differentiation of erythroid progenitor cells and the maintenance of a physiological level of circulating erythrocyte mass. It is a glycoprotein produced primarily by the kidney. The biological effects of EPO are mediated by the erythropoietin receptor (Epo R). Genetic variations in EPO is associated with susceptibility to microvascular complications of diabetes type 2 (MVCD2) (including diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease and diabetic neuropathy). It is used for the treatment of anemia and misused as a performance-enhancing drug in endurance athletes.
- NCBI Accession
- NP_000790
- Pathways
- JAK-STAT Signalweg, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
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