TGFA Protein

Produktnummer ABIN7536426

Recombinant TGFA-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für TGFA Protein (ABIN7536426)

Target: TGFA (Transforming Growth Factor, alpha (TGFA))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 92 % by SDS-PAGE.

Produktdetails

Verwendungszweck: Recombinant Human TGF-alpha/TGFA Protein

Sequenz: VVSHFNDCPD SHTQFCFHGT CRFLVQEDKP ACVCHSGYVG ARCEHADLLA

Spezifität: Val40-Ala89

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: <1EU/μg

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Konzentration: 0.3 mg/mL

Buffer: Lyophilized from a 0.22 μm filtered solution of 50 mM Tris,100 mM NaCl, pH 8.0

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Antigendetails

Target: TGFA (Transforming Growth Factor, alpha (TGFA))

Andere Bezeichnung: TGF-alpha/TGFA

Hintergrund:

Description: The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared to adjacent normal tissue and high TGFA gene expression strongly correlated with poor survival in patients with lung adenocarcinoma, and miR-374a suppresses lung adenocarcinoma cell proliferation and invasion via targeting TGFA gene expression. Transforming growth factor alpha (TGFA) is a well-characterized mammalian growth factor that might contribute to the development of Cleft lip and palate (CL/P).

Name: TFGA,TGF-alpha

Gen-ID: 7039

UniProt: P01135-1

Pathways: NF-kappaB Signalweg, RTK Signalweg, EGFR Signaling Pathway