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ADAM8 Protein (AA 1-653) (His tag)

ADAM8 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7505638
  • Target Alle ADAM8 Proteine anzeigen
    ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-653
    Spezies
    • 7
    • 2
    • 2
    Human
    Quelle
    • 7
    • 4
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses ADAM8 Protein ist gelabelt mit His tag.
    Sequenz
    Met1-Ser653
    Produktmerkmale
    A DNA sequence encoding the Human ADAM8 protein (P78325) (Met1-Ser653) was expressed with a C-His.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product ADAM8 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Haltbarkeit
    12 months
  • Target
    ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))
    Andere Bezeichnung
    ADAM8 (ADAM8 Produkte)
    Hintergrund

    Abbreviation: ADAM8,CD156a

    Target Synonym: Disintegrin and metalloproteinase domain-containing protein 8,ADAM 8,EC 3.4.24.,Cell surface antigen MS2,CD antigen CD156a,MS2

    Background: ADAM8, also known as cell surface antigen MS2 or CD156a, is a member of the ADAM family that contains a disintegrin and metalloprotease-like domain. ADAM8 can cleave a variety of substrates and has been shown as a sheddase for the low affinity IgE receptor CD23 and the neural recognition molecule CHL1. Expression and regulation studies suggest that ADAM8 is a novel osteoclast stimulating factor and may play a role in asthma. It can be activated and assayed under the conditions described in the Activity Assay Protocol.

    Molekulargewicht

    Calculated MW: 71.72 kDa

    Observed MW: 60 kDa

    UniProt
    P78325
    Pathways
    Activation of Innate immune Response, M Phase
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