BAG3 Protein (AA 421-498) (GST tag)

Produktnummer ABIN7505080

Dieses Recombinant BAG3-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für BAG3 Protein (AA 421-498) (GST tag) (ABIN7505080)

Target: BAG3 (BCL2-Associated Athanogene 3 (BAG3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 421-498

Aufreinigungstag / Konjugat: Dieses BAG3 Protein ist gelabelt mit GST tag.

Sequenz: Gly 421-Ala 498

Produktmerkmale: A DNA sequence encoding the Human BAG3 protein (O95817) (Gly 421-Ala 498) was expressed with a N-GST tag.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: BAG3 (BCL2-Associated Athanogene 3 (BAG3))

Andere Bezeichnung: BAG3

Hintergrund:

Abbreviation: BAG3

Target Synonym: BAG-3,Bag3,BAG3

Background: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70.

Molekulargewicht:

Calculated MW: 33.47 kDa

Observed MW: 35 kDa

UniProt: O95817