IL-13 Protein (GST tag)
Kurzübersicht für IL-13 Protein (GST tag) (ABIN7488947)
Target
Alle IL-13 (IL13) Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Aufreinigungstag / Konjugat
- Dieses IL-13 Protein ist gelabelt mit GST tag.
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Verwendungszweck
- Human IL-13 Protein, GST Tag
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Sequenz
- Gly 21 - Asn 132
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Produktmerkmale
- Human IL-13 Protein, GST Tag is expressed from human 293 cells (HEK293). It contains AA Gly 21 - Asn 132 (Accession # AAK53823.1).
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Endotoxin-Niveau
- 1.0 EU per μg
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Interleukin 13 (IL13) (AA 21-132) protein (His-Avi Tag)
IL13 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
Interleukin 13 (IL13) (AA 21-132) protein (Fc Tag)IL13 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 13 (IL13) (AA 19-132) protein (His tag)IL13 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 13 (IL13) (AA 26-131) (Active) protein (His tag)IL13 Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 13 (IL13) (AA 21-132) protein (His-Avi Tag,Biotin)IL13 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
Interleukin 13 (IL13) (AA 19-132) (Active) proteinIL13 Spezies: Human Wirt: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Interleukin 13 (IL13) (AA 21-132) (Active) protein (Fc Tag)IL13 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 13 (IL13) (AA 21-132) (Active) protein (His tag,AVI tag,Biotin)IL13 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 13 (IL13) protein (mFc Tag)IL13 Spezies: Human Wirt: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Interleukin 13 (IL13) (AA 22-131) protein (His tag)IL13 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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Kommentare
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This protein carries a GST tag at the C-terminus. (GST) The protein has a calculated MW of 39 kDa. The protein migrates as 48-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C
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- IL-13 (IL13) (Interleukin 13 (IL13))
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Andere Bezeichnung
- IL-13
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Hintergrund
- Interleukin 13 (IL13) is also known as ALRH, BHR1and P600, is a single-chain glycosylated polypeptide, and is a cytokine critical in regulating inflammatory and immune responses. IL13 is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. The functions of IL-13 overlap considerably with those of IL-4, especially with regard to changes induced on hematopoietic cells, but these effects are probably less important given the more potent role of IL-4. IL-13 induces matrix metalloproteinases (MMPs) as part of a mechanism that protects against excessive allergic inflammation that predisposes to asphyxiation. IL-13 induces many features of allergic lung disease, including airway hyperresponsiveness, goblet cell metaplasia and mucus hypersecretion, which all contribute to airway obstruction.
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Molekulargewicht
- 39 kDa
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Pathways
- JAK-STAT Signalweg, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
Target
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