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CNTF Protein

Recombinant CNTF-Protein exprimiert in Escherichia coli (E. coli).
Produktnummer ABIN7455693

Kurzübersicht für CNTF Protein (ABIN7455693)

Target

Alle CNTF Proteine anzeigen
CNTF (Ciliary Neurotrophic Factor (CNTF))

Protein-Typ

Recombinant

Spezies

  • 19
  • 8
  • 4
  • 2
  • 2
  • 2
Human

Quelle

  • 26
  • 3
  • 3
  • 2
  • 1
Escherichia coli (E. coli)

Reinheit

Greater than 95 % as determined by reducing SDS-PAGE.
  • Verwendungszweck

    Recombinant Human Ciliary Neurotrophic Factor is produced by our E.coli expression system and the target gene encoding Ala2-Met200 is expressed.

    Produktmerkmale

    Extracellular Domain Protein

    Aufreinigung

    Affinity purification
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    Expressionssystem
    Konjugat
    Origin
    Preis ab
    Expressionssystem HEK-293 Cells
    Konjugat His tag
    Origin Human
    Preis ab 12.620,45 €
    Expressionssystem Cell-free protein synthesis (CFPS)
    Konjugat Strep Tag
    Origin Human
    Preis ab 20.480,57 €

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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, pH 8.0.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Haltbarkeit

    12 months
  • Target

    CNTF (Ciliary Neurotrophic Factor (CNTF))

    Andere Bezeichnung

    CNTF

    Hintergrund

    Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83 % homology in their protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle cytokines share gp130 as a signal transducing subunit in their receptor complexes. CNTF, like FGF acidic, FGF basic, and PD-ECGF (platelet-derived endothelial cell growth factor), does not possess a signal sequence that would allow secretion of the factor by classical secretion pathways. The mechanism underlying the release of CNTF is unknown.

    Molekulargewicht

    22.93 KDa

    UniProt

    P26441

    Pathways

    JAK-STAT Signalweg
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