IL1RAP Protein (AA 21-359) (His tag)

Produktnummer ABIN7490911

Produktdetails

Target: IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

Protein-Typ: Recombinant

Proteineigenschaft: AA 21-359

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses IL1RAP Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant human IL1RAP protein with C-terminal 6xHis tag

Spezifität: IL1RAP (Ser21-Glu359) 6xHis tag

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Reinheit: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

Andere Bezeichnung: IL1RAP (IL1RAP Produkte)

Hintergrund: This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Jul 2018]

Molekulargewicht: predicted molecular mass of 39.9 kDa after removal of the signal peptide. The apparent molecular mass of IL1RAP-His is 55-70 kDa due to glycosylation.

UniProt: Q9NPH3

Pathways: NF-kappaB Signalweg, Growth Factor Binding