IL13 Receptor alpha 1 Protein (AA 26-340) (His tag)

Produktnummer ABIN7275043

Dieses Recombinant IL13 Receptor alpha 1-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für IL13 Receptor alpha 1 Protein (AA 26-340) (His tag) (ABIN7275043)

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 95 % as determined by Bis-Tris PAGE

Produktdetails

Proteineigenschaft: AA 26-340

Aufreinigungstag / Konjugat: Dieses IL13 Receptor alpha 1 Protein ist gelabelt mit His tag.

Verwendungszweck: Mouse IL-13Ra1 Protein

Sequenz: Ala26-Thr340

Produktmerkmale: Recombinant Mouse IL-13Ra1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala26-Thr340.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Mouse IL-13Ra1 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Andere Bezeichnung: IL-13Ra1

Hintergrund: Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2.

Molekulargewicht: 37.1 kDa. Due to glycosylation, the protein migrates to 50-68 kDa based on Bis-Tris PAGE result.

UniProt: O09030

Pathways: JAK-STAT Signalweg, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response