IL-15 Protein (AA 49-162)
Kurzübersicht für IL-15 Protein (AA 49-162) (ABIN7274953)
Target
Alle IL-15 (IL15) Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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    - 
                                            Proteineigenschaft
- AA 49-162
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                                            Verwendungszweck
- Human IL-15 Protein
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                                            Sequenz
- Asn49-Ser162
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                                            Produktmerkmale
- Recombinant Human IL-15 Protein is expressed from E.coli without tag., It contains Asn49-Ser162.
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                                            Sterilität
- 0.22 μm filtered
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                                            Endotoxin-Niveau
- Less than 0.05 EU per μg by the LAL method.
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                                            Biological Activity Comment
- Measured in a cell proliferation assay using CTLL2 cells. The ED50 for this effect is 0.1  0.3 ng/mL. The specific activity of recombinant human IL15 is > 1 x 10^7 units/mg, which is calibrated against the human IL15 reference standard (NIBSC code: 95/554). Test result was comparable to standard batch.
 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Format
- Lyophilized
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                                            Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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                                            Buffer
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4) / 20 mM Tris, 150 mM NACI ( pH 8.0). Normally 8 % trehalose is added as protectant before lyophilization.
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                                            Lagerung
- -20 °C,-80 °C
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                                            Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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                                            Haltbarkeit
- 12 months
 
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    - IL-15 (IL15) (Interleukin 15 (IL15))
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                                            Andere Bezeichnung
- IL-15
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                                            Hintergrund
- Interleukin 15 (IL-15) is a widely expressed 14 kDa cytokine that is structurally and functionally related to IL-2 and plays an important role in many immunological diseases. IL-15 is a cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA.
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                                            Molekulargewicht
- 12.8 kDa same as Tris-Bis PAGE result.
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                                            UniProt
- P40933
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                                            Pathways
- JAK-STAT Signalweg, Glycosaminoglycan Metabolic Process
 Target
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