IL-15 Protein (AA 49-162)
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- Target Alle IL-15 (IL15) Proteine anzeigen
- IL-15 (IL15) (Interleukin 15 (IL15))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 49-162
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Verwendungszweck
- Human IL-15 Protein
- Sequenz
- Asn49-Ser162
- Produktmerkmale
- Recombinant Human IL-15 Protein is expressed from E.coli without tag., It contains Asn49-Ser162.
- Reinheit
- >95 % as determined by Tris-Bis PAGE, > 95 % as determined by SEC-HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 0.05 EU per μg by the LAL method.
- Biological Activity Comment
- Measured in a cell proliferation assay using CTLL2 cells. The ED50 for this effect is 0.1 0.3 ng/mL. The specific activity of recombinant human IL15 is > 1 x 10^7 units/mg, which is calibrated against the human IL15 reference standard (NIBSC code: 95/554). Test result was comparable to standard batch.
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4) / 20 mM Tris, 150 mM NACI ( pH 8.0). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- IL-15 (IL15) (Interleukin 15 (IL15))
- Andere Bezeichnung
- IL-15 (IL15 Produkte)
- Hintergrund
- Interleukin 15 (IL-15) is a widely expressed 14 kDa cytokine that is structurally and functionally related to IL-2 and plays an important role in many immunological diseases. IL-15 is a cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA.
- Molekulargewicht
- 12.8 kDa same as Tris-Bis PAGE result.
- UniProt
- P40933
- Pathways
- JAK-STAT Signalweg, Glycosaminoglycan Metabolic Process
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