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IL-4 Protein (AA 25-153)

Dieses Recombinant IL-4-Protein wird in HEK-293 Cells produziert.
Produktnummer ABIN7274949

Kurzübersicht für IL-4 Protein (AA 25-153) (ABIN7274949)

Target

Alle IL-4 (IL4) Proteine anzeigen
IL-4 (IL4) (Interleukin 4 (IL4))

Protein-Typ

Recombinant

Spezies

  • 39
  • 27
  • 9
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Quelle

  • 56
  • 20
  • 16
  • 12
  • 5
  • 4
  • 2
HEK-293 Cells

Reinheit

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • Proteineigenschaft

    AA 25-153

    Verwendungszweck

    Human IL-4 Protein

    Sequenz

    His25-Ser153

    Produktmerkmale

    Recombinant Human IL-4 Protein is expressed from HEK293 without tag.It contains His25-Ser153.

    Sterilität

    0.22 μm filtered

    Endotoxin-Niveau

    Less than 1EU per μg by the LAL method.

    Biological Activity Comment

    Immobilized Human IL-4, No Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human IL-4 R alpha, hFc Tag with the EC50 of 9.8ng/ml determined by ELISA. See testing image for detail.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    Buffer

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    IL-4 (IL4) (Interleukin 4 (IL4))

    Andere Bezeichnung

    IL-4

    Hintergrund

    Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor.

    Molekulargewicht

    14.96 kDa. Due to glycosylation, the protein migrates to 23-25 kDa based on Tris-Bis PAGE result.

    UniProt

    P05112-1

    Pathways

    JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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