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IL-18 Protein (AA 37-193) (Biotin)

Dieses Recombinant IL-18-Protein wird in Escherichia coli (E. coli) exprimiert.
Produktnummer ABIN7274881

Kurzübersicht für IL-18 Protein (AA 37-193) (Biotin) (ABIN7274881)

Target

Alle IL-18 (IL18) Proteine anzeigen
IL-18 (IL18) (Interleukin 18 (IL18))

Protein-Typ

Recombinant

Spezies

  • 21
  • 8
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Quelle

  • 31
  • 9
  • 3
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Reinheit

> 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
  • Proteineigenschaft

    AA 37-193

    Aufreinigungstag / Konjugat

    Dieses IL-18 Protein ist gelabelt mit Biotin.

    Verwendungszweck

    Biotinylated Human IL-18 Protein (Primary Amine Labeling)

    Sequenz

    Tyr37-Asp193

    Produktmerkmale

    Recombinant Biotinylated Human IL-18 Protein (Primary Amine Labeling) is expressed from E.coli without tag.It contains Tyr37-Asp193.

    Sterilität

    0.22 μm filtered

    Endotoxin-Niveau

    Less than 1EU per μg by the LAL method.

    Biological Activity Comment

    Immobilized Human IL-18BP, hFc Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human IL-18, No Tag with the EC50 of 24.2ng/ml determined by ELISA. See testing image for detail.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Supplied as 0.22μm filtered solution in 20 mM PB, 250 mM NaCl, 50 mM L-arginine ( pH 7.4).

    Lagerung

    -80 °C

    Informationen zur Lagerung

    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    IL-18 (IL18) (Interleukin 18 (IL18))

    Andere Bezeichnung

    IL-18

    Hintergrund

    Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naive T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation.

    Molekulargewicht

    18.2 kDa same as Tris-Bis PAGE result.

    UniProt

    Q14116

    Pathways

    Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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