IL-18 Protein (AA 37-193) (Biotin)
Kurzübersicht für IL-18 Protein (AA 37-193) (Biotin) (ABIN7274881)
Target
Alle IL-18 (IL18) Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 37-193
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Aufreinigungstag / Konjugat
- Dieses IL-18 Protein ist gelabelt mit Biotin.
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Verwendungszweck
- Biotinylated Human IL-18 Protein (Primary Amine Labeling)
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Sequenz
- Tyr37-Asp193
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Produktmerkmale
- Recombinant Biotinylated Human IL-18 Protein (Primary Amine Labeling) is expressed from E.coli without tag.It contains Tyr37-Asp193.
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Sterilität
- 0.22 μm filtered
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Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Human IL-18BP, hFc Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human IL-18, No Tag with the EC50 of 24.2ng/ml determined by ELISA. See testing image for detail.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Supplied as 0.22μm filtered solution in 20 mM PB, 250 mM NaCl, 50 mM L-arginine ( pH 7.4).
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- IL-18 (IL18) (Interleukin 18 (IL18))
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Andere Bezeichnung
- IL-18
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Hintergrund
- Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naive T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation.
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Molekulargewicht
- 18.2 kDa same as Tris-Bis PAGE result.
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UniProt
- Q14116
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
Target
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