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CD70 Protein (Trimer) (His tag)

CD70 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Produktnummer ABIN7274322
  • Target Alle CD70 Proteine anzeigen
    CD70 (CD70 Molecule (CD70))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Trimer
    Spezies
    • 32
    • 10
    • 1
    • 1
    • 1
    Human
    Quelle
    • 26
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses CD70 Protein ist gelabelt mit His tag.
    Sequenz
    Leu50-Pro193
    Reinheit
    > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human CD27 Ligand (Trimer) at 2μg/ml (100μl/Well) on the plate. Dose response curve for Human CD27, hFc Tag with the EC50 of 63.8ng/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product CD70 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CD70 (CD70 Molecule (CD70))
    Andere Bezeichnung
    CD27 Ligand (CD70 Produkte)
    Hintergrund
    CD70 Molecule, CD70, TNFSF7, CD27 Ligand, CD27-L, CD27LG, Ki-24 antigen, TNFSF7G,CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
    Molekulargewicht
    51.8 kDa. Due to glycosylation, the protein migrates to 62-65 kDa based on Tris-Bis PAGE result.
    Pathways
    Cancer Immune Checkpoints
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