CD70 Protein (Trimer) (His tag)
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- Target Alle CD70 Proteine anzeigen
- CD70 (CD70 Molecule (CD70))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- Trimer
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses CD70 Protein ist gelabelt mit His tag.
- Sequenz
- Leu50-Pro193
- Reinheit
- > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human CD27 Ligand (Trimer) at 2μg/ml (100μl/Well) on the plate. Dose response curve for Human CD27, hFc Tag with the EC50 of 63.8ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product CD70 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
- Lagerung
- 4 °C,-80 °C
- Informationen zur Lagerung
- Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CD70 (CD70 Molecule (CD70))
- Andere Bezeichnung
- CD27 Ligand (CD70 Produkte)
- Hintergrund
- CD70 Molecule, CD70, TNFSF7, CD27 Ligand, CD27-L, CD27LG, Ki-24 antigen, TNFSF7G,CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
- Molekulargewicht
- 51.8 kDa. Due to glycosylation, the protein migrates to 62-65 kDa based on Tris-Bis PAGE result.
- Pathways
- Cancer Immune Checkpoints
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