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CD86 Protein (CD86) (His tag)

Dieses Recombinant CD86-Protein wird in Human Cells exprimiert.
Produktnummer ABIN7320996

Kurzübersicht für CD86 Protein (CD86) (His tag) (ABIN7320996)

Target

Alle CD86 Proteine anzeigen
CD86

Protein-Typ

Recombinant

Spezies

  • 25
  • 13
  • 5
  • 3
  • 3
  • 3
Rhesusaffen

Quelle

  • 24
  • 10
  • 6
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human Cells

Reinheit

> 95 % as determined by reducing SDS-PAGE.
  • Aufreinigungstag / Konjugat

    Dieses CD86 Protein ist gelabelt mit His tag.

    Verwendungszweck

    Recombinant Rhesus macaque B7-2/CD86 Protein (His Tag)

    Sequenz

    Tyr31-Pro247

    Produktmerkmale

    Recombinant Rhesus macaque CD86 is produced by our Mammalian expression system and the target gene encoding Tyr31-Pro247 is expressed with a 6His tag at the C-terminus.

    Endotoxin-Niveau

    < 1.0 EU per μg as determined by the LAL method.
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  • Kommentare

    40-90 kDa

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Lagerung

    4 °C,-20 °C,-80 °C

    Informationen zur Lagerung

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    CD86

    Andere Bezeichnung

    B7-2/CD86

    Hintergrund

    Background: T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. It is highly expressed on activated antigen presenting cells. CD86 involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.

    Synonym: T-lymphocyte activation antigen CD86 isoform 1,Activation B7-2 antigen, CD86

    Molekulargewicht

    25.7 kDa

    UniProt

    H9ZFI8

    Pathways

    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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