Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

UNG Protein (GST tag)

Dieses Recombinant UNG-Protein wird in Escherichia coli (E. coli) produziert.
Produktnummer ABIN7317329

Kurzübersicht für UNG Protein (GST tag) (ABIN7317329)

Target

Alle UNG Proteine anzeigen
UNG (Uracil-DNA Glycosylase (UNG))

Protein-Typ

Recombinant

Spezies

  • 6
  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Quelle

  • 93
  • 5
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Reinheit

> 90 % as determined by reducing SDS-PAGE.
  • Aufreinigungstag / Konjugat

    Dieses UNG Protein ist gelabelt mit GST tag.

    Verwendungszweck

    Recombinant Human Uracil-DNA glycosylase/UNG Protein (GST Tag)

    Sequenz

    Phe 85-Leu 304

    Produktmerkmale

    A DNA sequence encoding the human UNG isoform 1 (P13051-2) (Phe 85-Leu 304) was fused with the GST tag at the N-terminus.
  • Möchten Sie weitere Optionen für dieses Protein ?

    !
    Entdecken Sie unsere vordefinierten maßgeschneiderten Proteine und Proteinservices!
    Produkt
    Expressionssystem
    Konjugat
    Origin
    Preis ab
    Expressionssystem HEK-293 Cells
    Konjugat His tag
    Origin Human
    Preis ab 13.711,36 €
    Expressionssystem Cell-free protein synthesis (CFPS)
    Konjugat Strep Tag
    Origin Human
    Preis ab 20.480,57 €

    Ihr Projekt erfordert weitere Anpassungen? Kontaktieren Sie uns und entdecken Sie unsere maßgeschneiderten Proteinlösungen

  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from sterile 40 mM Tris, 0.15M NaCl, 2 mM GSH, pH 7.5

    Lagerung

    4 °C,-20 °C,-80 °C

    Informationen zur Lagerung

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    UNG (Uracil-DNA Glycosylase (UNG))

    Andere Bezeichnung

    Uracil-DNA glycosylase/UNG

    Substanzklasse

    Viral Protein

    Hintergrund

    Background: Isoform 1 is widely expressed with the highest expression in skeletal muscle, heart and testicles. Isoform 2 has the highest expression levels in tissues containing proliferating cells. Uracil-DNA glycosylase exists in two forms: mitochondrial uracil-DNA glycosylase 1 (UNG1) and nuclear uracil-DNA glycosylase 2 (UNG2). uracil-DNA glycosylase. This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. Defects in UNG are a cause of immunodeficiency with hyper-IgM type 5 (HIGM5). A rare immunodeficiency syndrome characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE. It results in a profound susceptibility to bacterial infections.

    Synonym: DGU,HIGM4,HIGM5,UDG,UNG1,UNG15,UNG2

    Molekulargewicht

    52 kDa

    Pathways

    DNA Reparatur, Production of Molecular Mediator of Immune Response
Sie sind hier:
Chat with us!