MBL2 Protein (AA 19-244)

Produktnummer ABIN7320615

Dieses Recombinant MBL2-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für MBL2 Protein (AA 19-244) (ABIN7320615)

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 19-244

Verwendungszweck: Recombinant Mouse MBL2/MBP-C Protein

Sequenz: Glu19-Asp244

Produktmerkmale: Recombinant Mouse Mannose Binding Lectin 2 is produced by our Mammalian expression system and the target gene encoding Glu19-Asp244 is expressed.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Andere Bezeichnung: MBL2/MBP-C

Hintergrund: MBL-2,Mannose Binding Lectin 2,Mannose binding lectin (C),Mannose-binding protein C,Mbl2,isoform CRA_b,Mannose-binding Lectin (MBL) is an acute phase protein bearing to the family of collectins produced by the liver as a monomer that forms a triple helix. Once released in serum, it further polymerizes forming dimers to octamers. The degree of serum polymerization is critical for the biological activity of MBL. MBL has higher affinity to microbial polysaccharides or their glycoconjugates. MBL was shown earlier to bind cell surfaces of bacteria, fungi, protozoa and viruses and acts as an acute-phase plasma protein (APP) during infection and inflammation. MBL activates the lectin-complement pathway, promotes opsonophagocytosis and modulates inflammation.

Molekulargewicht:

Calculated MW: 24.0 kDa

Observed MW: 28 kDa

UniProt: Q3UEK1

Pathways: Komplementsystem, Positive Regulation of Immune Effector Process