Kallikrein 11 Protein (KLK11) (AA 19-250) (His tag)
Kurzübersicht für Kallikrein 11 Protein (KLK11) (AA 19-250) (His tag) (ABIN7319354)
Target
Alle Kallikrein 11 (KLK11) Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 19-250
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Aufreinigungstag / Konjugat
- Dieses Kallikrein 11 Protein ist gelabelt mit His tag.
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Verwendungszweck
- Recombinant Human Kallikrein 11/KLK11 Protein (His Tag)
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Sequenz
- Glu19-Asn250
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Produktmerkmale
- Recombinant Human Kallikrein 11 is produced by our Mammalian expression system and the target gene encoding Glu19-Asn250 is expressed with a 6His tag at the C-terminus.
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 2 mM CaCl2, pH 8.0.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Haltbarkeit
- 6 months
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- Kallikrein 11 (KLK11)
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Andere Bezeichnung
- Kallikrein 11/KLK11
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Hintergrund
- Hippostasin,KLK11,Kallikrein-11,PRSS20,Serine Protease 20,TLSP,Trypsin-Like Protease,hK11,Human Kallikrein 11 (KLK11) is a member of tissue kallikrein family which are extracellular serine proteases consisting of 15 members. Two isoforms of KLK11 are differentially expressed. Isoform 1 is predominantly expressed in brain and isoform 2 is preferentially expressed in prostate. Isoform 1 consists of a signal peptide,a short pro peptide and the mature chain.Isoform 2 contains an extra 32 amino acid N terminal to full-length isoform 1.KLK11 is a novel marker for ovarian and prostate cancer carcinomas. KLK11 can be activated by thermolysin and is active against a thioester substrate.
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Molekulargewicht
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Calculated MW: 26.3 kDa
Observed MW: 38 kDa
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NCBI Accession
- NP_006844
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Pathways
- Komplementsystem
Target
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