Kallikrein 11 Protein (KLK11) (His tag)

Produktnummer ABIN7320113

Recombinant Kallikrein 11-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für Kallikrein 11 Protein (KLK11) (His tag) (ABIN7320113)

Target: Kallikrein 11 (KLK11)

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses Kallikrein 11 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse Kallikrein 11/KLK11 Protein (His Tag)

Sequenz: Met 1-Asn 276

Produktmerkmale: A DNA sequence encoding the mouse KLK11 isoform 2 (Q9QYN3) (Met 1-Asn 276), was fused with a C-terminal polyhistidine tag.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: Kallikrein 11 (KLK11)

Andere Bezeichnung: Kallikrein 11/KLK11

Hintergrund: 2310015I08Rik,Prss20,TLSP,kallikrein-related peptidase 11 (KLK11), also known as hippostasin, trypsin-like serine protease and PRSS20, is a member of human tissue kallikrein family. It is a subgroup of serine proteases with diverse physiological functions, which is implicated in carcinogenesis and some with potential that serving as novel biomarkers for ovarian and prostate cancer and other diseases. The KLK11 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Two alternatively spliced forms exist, resulting in 250 (isoform 1) and 282 (isoform 2) amino acid sequences. Isoform 2 is identical to isoform 1, except for an inserted 32 amino acid segment. Isoform 1 is predominantly expressed in brain whereas isoform 2 is preferentially expressed in prostate.

Molekulargewicht:

Calculated MW: 27.3 kDa

Observed MW: 38-42 kDa

UniProt: Q9QYN3

Pathways: Komplementsystem