IL7R Protein (Fc Tag)
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- Target Alle IL7R Proteine anzeigen
- IL7R (Interleukin 7 Receptor (IL7R))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Maus
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Quelle
- Human Cells
- Aufreinigungstag / Konjugat
- Dieses IL7R Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- Recombinant Mouse IL7RA/CD127 Protein (Fc Tag)(Active)
- Sequenz
- Glu21-Asp239
- Produktmerkmale
- Recombinant Mouse Interleukin-7 receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Glu21-Asp239 is expressed with a Fc tag at the C-terminus.
- Reinheit
- > 95 % as determined by SDS-PAGE
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human IL-7-His(Cat: PKSH032654) at 10μg/ml(100 μl/well) can bind Mouse IL-7RA-Fc.
- Top Product
- Discover our top product IL7R Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- IL7R (Interleukin 7 Receptor (IL7R))
- Andere Bezeichnung
- IL7RA/CD127 (IL7R Produkte)
- Hintergrund
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Background: Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses.
Synonym: Interleukin-7 receptor subunit alpha, Il7r, IL-7 receptor subunit alpha, IL-7R subunit alpha, IL-7R-alpha, IL-7RA, CD127,IL-7Ralpha
- Molekulargewicht
- 52.1 kDa
- NCBI Accession
- NP_032398
- Pathways
- JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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