IL-13 Protein (mFc Tag)

Produktnummer ABIN7319863

Recombinant IL-13-Protein exprimiert in Human Cells.

Kurzübersicht für IL-13 Protein (mFc Tag) (ABIN7319863)

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Reinheit: >95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses IL-13 Protein ist gelabelt mit mFc Tag.

Verwendungszweck: Recombinant Human Interleukin-13/IL-13 (C-mFc)

Sequenz: Gly21--Asn132

Produktmerkmale: Recombinant Human Interleukin-13 is produced by our Mammalian expression system and the target gene encoding Gly21-Asn132 is expressed with a mFc tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Andere Bezeichnung: Interleukin-13/IL-13

Hintergrund:

Background: Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.

Synonym: Interleukin-13, IL-13

Molekulargewicht: 38.7 kDa

Pathways: JAK-STAT Signalweg, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport