GAS6 Protein (His tag)
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- Target Alle GAS6 Proteine anzeigen
- GAS6 (Growth Arrest-Specific 6 (GAS6))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- Human Cells
- Aufreinigungstag / Konjugat
- Dieses GAS6 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human GAS6 (C-6His)
- Sequenz
- Ala31-Ala678
- Produktmerkmale
- Recombinant Human Growth Arrest-specific Protein 6 is produced by our Mammalian expression system and the target gene encoding Ala31-Ala678 is expressed with a 6His tag at the C-terminus.
- Reinheit
- >95 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human AXL-His (Cat#C02B) at 10μg/ml (100 μl/well) can bind Human GAS6-His* (Cat#C01W).*: Biotinylated by NHS-biotin prior to testing.The ED50 of Recombinant Human GAS6-His* (Cat#C01W) is 0.04466 ug/ml.
- Top Product
- Discover our top product GAS6 Protein
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Growth Arrest-Specific 6 (GAS6) (AA 31-637) protein (His tag)
GAS6 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Arrest-Specific 6 (GAS6) (AA 49-678) protein (His tag)GAS6 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Arrest-Specific 6 (GAS6) (AA 31-678) protein (His tag)GAS6 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Growth Arrest-Specific 6 (GAS6) (AA 1-678) protein (GST tag)GAS6 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Growth Arrest-Specific 6 (GAS6) (AA 136-311) (Active) protein (His tag)GAS6 Spezies: Human Wirt: Escherichia coli (E. coli) > 90 % AcA, CC Active
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of PBS, 10 % Glycerol, pH 7.4.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- GAS6 (Growth Arrest-Specific 6 (GAS6))
- Andere Bezeichnung
- GAS6 (GAS6 Produkte)
- Hintergrund
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Background: GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
Synonym: AXLLG, AXLLGAXL stimulatory factor, AXSFAXL receptor tyrosine kinase ligand, Gas6, GAS-6, growth arrest-specific 6, growth arrest-specific protein 6
- Molekulargewicht
- 72.7 kDa
- UniProt
- Q14393
- Pathways
- RTK Signalweg, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
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