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GZMB Protein (His tag)

GZMB Spezies: Maus Wirt: Human Cells Recombinant > 85 % as determined by SDS-PAGE
Produktnummer ABIN7320540
  • Target Alle GZMB Proteine anzeigen
    GZMB (Granzyme B (GZMB))
    Protein-Typ
    Recombinant
    Spezies
    • 11
    • 7
    • 3
    • 1
    • 1
    Maus
    Quelle
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses GZMB Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Mouse Granzyme B(G,H)/GZMB Protein (His Tag)
    Sequenz
    Gly19-Ser247
    Produktmerkmale
    Recombinant Mouse Granzyme B is produced by our Mammalian expression system and the target gene encoding Gly19-Ser247 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 85 % as determined by SDS-PAGE
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product GZMB Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    GZMB (Granzyme B (GZMB))
    Andere Bezeichnung
    Granzyme B/GZMB (GZMB Produkte)
    Synonyme
    CCPI Protein, CGL-1 Protein, CGL1 Protein, CSP-B Protein, CSPB Protein, CTLA1 Protein, CTSGL1 Protein, HLP Protein, SECT Protein, granzyme B Protein, GZMB Protein
    Hintergrund

    Background: Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

    Synonym: Granzyme B(G,H),CTLA-1,Cytotoxic cell protease 1,CCP1,Fragmentin-2,Gzmb,Ctla-1, Ctla1

    Molekulargewicht
    26.5 kDa
    UniProt
    P04187
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose
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