Glucagon Protein (GCG) (His tag)
Kurzübersicht für Glucagon Protein (GCG) (His tag) (ABIN7318536)
Target
Alle Glucagon (GCG) Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Aufreinigungstag / Konjugat
- Dieses Glucagon Protein ist gelabelt mit His tag.
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Verwendungszweck
- Recombinant Human Glucagon/GCG Protein (His Tag)
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Sequenz
- Arg21-Lys180
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Produktmerkmale
- Recombinant Human Glucagon is produced by our Mammalian expression system and the target gene encoding Arg21-Lys180 is expressed with a 6His tag at the C-terminus.
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Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
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Glucagon (GCG) (AA 90-180) protein (His tag)
GCG Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Glucagon (GCG) (AA 21-180) protein (His-IF2DI Tag)GCG Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Glucagon (GCG) (AA 1-180) protein (GST tag)GCG Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,200 mM NaCl,1 mM DTT,50 % Glycerol, pH 8.0.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Glucagon (GCG)
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Andere Bezeichnung
- Glucagon/GCG
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Hintergrund
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Background: Glucagon is a secreted protein and belongs to the glucagon family. Glucagon can be cleved into 8 chains, playing an important role in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon can regulates blood glucose by decreasing glycolysis and increasing gluconeogenesis. In addition, Glucagon is involved in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon release is stimulated by hypoglycemia and inhibited by hyperglycemia, insulin, and somatostatin. In the glucagon antagonist, His-53 and Phe-58 are missing. This antagonist has been successfully utilized to reduce glucose concentration in vivo.
Synonym: Glucagon, Glicentin, Glicentin-Related Polypeptide, GRPP, Oxyntomodulin, OXM, OXY, Glucagon, Glucagon-Like Peptide 1, GLP-1, Incretin Hormone, Glucagon-like Peptide 1, GLP-1, Glucagon-Like Peptide 2, GLP-2, GCG
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Molekulargewicht
- 18.6 kDa
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UniProt
- P01275
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Pathways
- Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling
Target
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